Regulated cell death is a vital and dynamic process in multicellular organisms that maintains
tissue homeostasis and eliminates potentially dangerous cells. Apoptosis, one of the better …

Triple-negative breast cancer (TNBC) is a subtype of human breast cancer with one of the
worst prognoses, with no targeted therapeutic strategies currently available. Regulated cell …

Small-cell lung cancer (SCLC) has traditionally been considered a recalcitrant cancer with a
dismal prognosis, with only modest advances in therapeutic strategies over the past several …

Cancer is one of the major causes of death and a significant obstacle to increasing life
expectancy worldwide. Chemotherapy remains the first-line adjuvant therapeutic option for …

Gene set enrichment is a mainstay of functional genomics, but it relies on gene function
databases that are incomplete. Here we evaluate five large language models (LLMs) for …

Countless expectations converge in the multidisciplinary endeavour for the search and
development of effective and safe drugs in fighting cancer. Although they still embody a …

Adoptive cell therapies engineered to express chimeric antigen receptors (CARs) or
transgenic T cell receptors (TCRs) to recognize and eliminate cancer cells have emerged as …

Due to their key role in the pathogenesis of cancer through the regulation of apoptosis, the B-
cell leukemia/lymphoma-2 (BCL-2) family proteins have been an attractive target for cancer …

Cancer has always been a worldwide problem, and the application of radiotherapy has
greatly improved the survival rate of cancer patients. Radiotherapy can modulate multiple …

Nanotherapeutics demonstrate poor accumulation in the tumor microenvironment due to
poor extravasation and penetration into the tumor. Therapeutics such as oligonucleotides …