Understanding the chemical exposome during fetal development and early childhood: a review

M Krausová, D Braun… - Annual Review of …, 2023 - annualreviews.org
Early human life is considered a critical window of susceptibility to external exposures.
Infants are exposed to a multitude of environmental factors, collectively referred to as the …

[HTML][HTML] Sample preparation strategies for mass spectrometry analysis in human exposome research: current status and future perspectives

Y Gu, JT Peach, B Warth - TrAC Trends in Analytical Chemistry, 2023 - Elsevier
The exposome is the measure of total environmental exposures and has a significant impact
on human health outcomes. Exposomics research typically examines complex biological …

Phospholipid removal for enhanced chemical exposomics in human plasma

K Sdougkou, H Xie, S Papazian… - Environmental …, 2023 - ACS Publications
The challenge of chemical exposomics in human plasma is the 1000-fold concentration gap
between endogenous substances and environmental pollutants. Phospholipids are the …

Low transplacental transfer of PFASs in the small-for-gestational-age (SGA) new-borns: Evidence from a Chinese birth cohort

Y Fan, L Guo, R Wang, J Xu, Y Fang, W Wang, J Lv… - Chemosphere, 2023 - Elsevier
Early life in utero exposure to per-and polyfluoroalkyl substances (PFASs) and infiltration
through the placenta into cord blood pose significant risk to fetal development. Accumulating …

Target exposome for characterizing early gestational exposure to contaminants of emerging concern and association with gestational diabetes mellitus

W Huang, XF Pan, S Tang, F Sun, P Wu… - Environmental …, 2023 - ACS Publications
Characterization of gestational exposure to complex contaminants of emerging concern
(CECs) is critical to the identification of environmental risk factors for pregnancy …

[HTML][HTML] Longitudinal biomonitoring of mycotoxin exposure during pregnancy in the Yale Pregnancy Outcome Prediction Study

M Krausová, KI Ayeni, Y Gu, Y Borutzki, J O'Bryan… - Environment …, 2024 - Elsevier
Mycotoxins are fungal toxins that may trigger adverse health effects in pregnant women and
their unborn children. Yet, data is scarce on the dynamic exposure patterns of mycotoxins in …

Screening Novel Per-and Polyfluoroalkyl Substances in Human Blood Based on Nontarget Analysis and Underestimated Potential Health Risks

X Chen, Z Lv, Y Yang, R Yang, G Shan… - … Science & Technology, 2023 - ACS Publications
Nontarget analysis has gained prominence in screening novel perfluoroalkyl and
polyfluoroalkyl substances (PFASs) in the environment, yet remaining limited in human …

Longitudinal exposomics in a multiomic wellness cohort reveals distinctive and dynamic environmental chemical mixtures in blood

K Sdougkou, S Papazian, B Bonnefille… - Environmental …, 2024 - ACS Publications
Chemical exposomes can now be comprehensively measured in human blood, but
knowledge of their variability and longitudinal stability is required for robust application in …

Association of maternal metals exposure, metabolites and birth outcomes in newborns: A prospective cohort study

S Zhao, X Yang, Q Xu, H Li, Y Su, Q Xu, QX Li… - Environment …, 2023 - Elsevier
Background Maternal exposure to metals may pose a risk to the health of newborns,
however, the underlying mechanisms remain ambiguous. Herein, we aimed to investigate …

Unraveling the fate of mycotoxins during the production of legume protein and other derived products

MA Pavicich, L Roose, C Meerpoel, K Raes… - npj Science of …, 2024 - nature.com
Consumers are increasingly looking for healthier and sustainable diets. Plant-based diets
rich in legumes satisfy this demand. Legumes contain protein, dietary fibers and starch …