Histotripsy: the first noninvasive, non-ionizing, non-thermal ablation technique based on ultrasound

Z Xu, TL Hall, E Vlaisavljevich… - International Journal of …, 2021 - Taylor & Francis
Histotripsy is the first noninvasive, non-ionizing, and non-thermal ablation technology
guided by real-time imaging. Using focused ultrasound delivered from outside the body …

Novel approaches to combat medical device-associated biofilms

X Li, L Sun, P Zhang, Y Wang - Coatings, 2021 - mdpi.com
Biofilms are aggregates formed as a protective survival state by microorganisms to adapt to
the environment and can be resistant to antimicrobial agents and host immune responses …

The histotripsy spectrum: differences and similarities in techniques and instrumentation

RP Williams, JC Simon, VA Khokhlova… - International Journal …, 2023 - Taylor & Francis
Since its inception about two decades ago, histotripsy–a non-thermal mechanical tissue
ablation technique–has evolved into a spectrum of methods, each with distinct potentiating …

Modeling tissue-selective cavitation damage

L Mancia, E Vlaisavljevich, N Yousefi… - Physics in Medicine …, 2019 - iopscience.iop.org
The destructive growth and collapse of cavitation bubbles are used for therapeutic purposes
in focused ultrasound procedures and can contribute to tissue damage in traumatic injuries …

Biofilms and effective porosity of hernia mesh: are they silent assassins?

ASW Jacombs, A Karatassas, B Klosterhalfen… - Hernia, 2020 - Springer
Purpose The purpose of this paper is to communicate two new concepts with the potential to
cause major morbidity in hernia repair, effective porosity and biofilm. These 2 concepts are …

Nominal Versus Actual Spatial Resolution: Comparison of Directivity and Frequency-Dependent Effective Sensitive Element Size for Membrane, Needle, Capsule, and …

KA Wear, A Shah - IEEE Transactions on Ultrasonics …, 2022 - ieeexplore.ieee.org
Frequency-dependent effective sensitive element radius is a key parameter for elucidating
physical mechanisms of hydrophone operation. In addition, it is essential to know to correct …

Focused ultrasound biofilm ablation: investigation of histotripsy for the treatment of catheter-associated urinary tract infections (CAUTIs)

C Childers, C Edsall, J Gannon… - IEEE Transactions …, 2021 - ieeexplore.ieee.org
Urinary catheters often become contaminated with biofilms, resulting in catheter-associated
urinary tract infections (CAUTIs) that adversely affect patient outcomes. Histotripsy is a …

[HTML][HTML] Particle-mediated histotripsy for the targeted treatment of intraluminal biofilms in catheter-based medical devices

DY Yuksel, L KlibanovAlexander - BME frontiers, 2022 - spj.science.org
Objective. This paper is an initial work towards developing particle-mediated histotripsy
(PMH) as a novel method of treating catheter-based medical device (CBMD) intraluminal …

The penetration effect of HMME-mediated low-frequency and low-intensity ultrasound against the Staphylococcus aureus bacterial biofilm

T Wang, W Ma, Z Jiang, L Bi - European Journal of Medical Research, 2020 - Springer
Background The purpose of this study was to observe the effect of hematoporphyrin
monomethyl ether (HMME)-mediated low-frequency and low-intensity ultrasound on mature …

Histotripsy: an innovative approach for minimally invasive tumour and disease treatment

MF Iqbal, MA Shafique, MA Raqib… - Annals of Medicine …, 2024 - journals.lww.com
Histotripsy is a noninvasive medical technique that uses high-intensity focused ultrasound
(HIFU) to treat liver tumours. The two main histotripsy methods are boiling histotripsy and …