Ecology and evolution of Mycobacterium tuberculosis
S Gagneux - Nature Reviews Microbiology, 2018 - nature.com
Tuberculosis (TB) is the number one cause of human death due to an infectious disease.
The causative agents of TB are a group of closely related bacteria known as the …
The causative agents of TB are a group of closely related bacteria known as the …
Tuberculosis caused by Mycobacterium africanum: Knowns and unknowns
ML Silva, B Cá, NS Osório, PNS Rodrigues… - PLoS …, 2022 - journals.plos.org
Tuberculosis (TB), one of the deadliest threats to human health, is mainly caused by 2 highly
related and human-adapted bacteria broadly known as Mycobacterium tuberculosis and …
related and human-adapted bacteria broadly known as Mycobacterium tuberculosis and …
Mycobacterium tuberculosis lineage 4 comprises globally distributed and geographically restricted sublineages
Generalist and specialist species differ in the breadth of their ecological niches. Little is
known about the niche width of obligate human pathogens. Here we analyzed a global …
known about the niche width of obligate human pathogens. Here we analyzed a global …
Phylogenomics of Mycobacterium africanum reveals a new lineage and a complex evolutionary history
Human tuberculosis (TB) is caused by members of the Mycobacterium tuberculosis complex
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …
(MTBC). The MTBC comprises several human-adapted lineages known as M. tuberculosis …
Differential rates of Mycobacterium tuberculosis transmission associate with host–pathogen sympatry
MI Gröschel, FJ Pérez-Llanos, R Diel, R Vargas Jr… - Nature …, 2024 - nature.com
Several human-adapted Mycobacterium tuberculosis complex (Mtbc) lineages exhibit a
restricted geographical distribution globally. These lineages are hypothesized to transmit …
restricted geographical distribution globally. These lineages are hypothesized to transmit …
The Nature and Evolution of Genomic Diversity in the Mycobacterium tuberculosis Complex
Abstract The Mycobacterium tuberculosis Complex (MTBC) consists of a clonal group of
several mycobacterial lineages pathogenic to a range of different mammalian hosts. In this …
several mycobacterial lineages pathogenic to a range of different mammalian hosts. In this …
Geospatial distribution of Mycobacterium tuberculosis genotypes in Africa
Objective To investigate the distribution of Mycobacterium tuberculosis genotypes across
Africa. Methods The SITVIT2 global repository and PUBMED were searched for spoligotype …
Africa. Methods The SITVIT2 global repository and PUBMED were searched for spoligotype …
Macrophage susceptibility to infection by Ghanaian Mycobacterium tuberculosis complex lineages 4 and 5 varies with self-reported ethnicity
S Osei-Wusu, JKA Tetteh, AB Musah… - Frontiers in Cellular …, 2023 - frontiersin.org
Background The epidemiology of Mycobacterium tuberculosis complex (MTBC) lineage 5
(L5) infections in Ghana revealed a significantly increased prevalence in Ewes compared to …
(L5) infections in Ghana revealed a significantly increased prevalence in Ewes compared to …
Evolution of Mycobacterium tuberculosis drug resistance in the genomic era
Mycobacterium tuberculosis has acquired drug resistance to all drugs that have been used
against it, including those only recently introduced into clinical practice. Compared to other …
against it, including those only recently introduced into clinical practice. Compared to other …
Bacterial diversity dominates variable macrophage responses of tuberculosis patients in Tanzania
H Hiza, M Zwyer, J Hella, A Arbués, M Sasamalo… - Scientific Reports, 2024 - nature.com
The Mycobacterium tuberculosis complex (MTBC) comprises nine human-adapted lineages
that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to …
that differ in their geographical distribution. Local adaptation of specific MTBC genotypes to …