Individuals who maintain cognitive function despite high levels of Alzheimer's disease (AD)-
associated pathology are said to be 'resilient'to AD. Identifying mechanisms underlying …

Sex and gender—biological and social constructs—significantly impact the prevalence of
protective and risk factors, influencing the burden of Alzheimer's disease (AD; amyloid beta …

Cognitive reserve and related constructs are valuable for aging-related research, but
consistency and clarification of terms is needed as there is still no universally agreed upon …

The ATN framework proposes a shift from a syndrome to a biological construct of Alzheimer
disease (AD) for research purposes. 1 According to this framework, whereAstands for …

Background Cognitive reserve and resilience are terms used to explain interindividual
variability in maintenance of cognitive health in response to adverse factors, such as brain …

Alzheimer's disease is the most common cause of dementia, gradually impairing memory,
intellectual, learning, and organizational capacities. An individual's capacity to perform …

Background and objective Cognitive and physical functions correlate and delineate aging
and disease trajectories. Whereas cognitive reserve (CR) is well-established, physical …

Introduction Cognitive resilience (CR) can be defined as the continuum of better through
worse than expected cognition, given the degree of neuropathology. The relation of healthy …

Abstract Background In Alzheimer's disease (AD), the associations between tau pathology
and brain atrophy and cognitive decline are well established, but imperfect. We investigate …

Mechanisms of resilience against tau pathology in individuals across the Alzheimer's
disease spectrum are insufficiently understood. Longitudinal data are necessary to reveal …