Treatable traits in airway disease: from theory to practice

A Agusti, PG Gibson, VM McDonald - The Journal of Allergy and Clinical …, 2023 - Elsevier
Chronic airway diseases such as asthma and chronic obstructive pulmonary disease are
prevalent and complex conditions that often coexist in the same patient. To address this …

An update on outcomes for COPD pharmacological trials: a COPD investigators report-reassessment of the 2008 American Thoracic Society/European Respiratory …

M Cazzola, P Rogliani, PJ Barnes, F Blasi… - American Journal of …, 2023 - atsjournals.org
Background: In 2008, a dedicated American Thoracic Society/European Respiratory Society
task force published a paper on the possible use and limitations of clinical outcomes and …

Lung Inflammation in alpha-1-antitrypsin deficient individuals with normal lung function

N Kokturk, N Khodayari, J Lascano, EL Riley… - Respiratory …, 2023 - Springer
Abstract Background Alpha-1-antitrypsin deficient (AATD) individuals are prone to develop
early age of onset chronic obstructive pulmonary disease (COPD) more severe than non …

Can Treatable Traits Be the Approach to Addressing the Complexity and Heterogeneity of COPD?

M Cazzola, P Rogliani, F Blasi - International Journal of Chronic …, 2023 - Taylor & Francis
The complexity of COPD implies the need to identify groups of patients with similar clinical
characteristics and prognosis or treatment requirements. This is why much attention has …

RETRO-POPE: A Retrospective, Multicenter, Real-World Study of All-Cause Mortality in COPD

V Koblizek, B Milenkovic, M Svoboda… - … Journal of Chronic …, 2023 - Taylor & Francis
Purpose The Phenotypes of COPD in Central and Eastern Europe (POPE) study assessed
the prevalence and clinical characteristics of four clinical COPD phenotypes, but not …

Impulse Oscillometry as a Diagnostic Test for Pulmonary Emphysema in a Clinical Setting

A Klitgaard, A Løkke, O Hilberg - Journal of Clinical Medicine, 2023 - mdpi.com
Body plethysmography (BP) is the standard pulmonary function test (PFT) in pulmonary
emphysema diagnosis, but not all patients can cooperate to this procedure. An alternative …

[HTML][HTML] The presence of extra-pulmonary treatable traits increases the likelihood of responding to pulmonary rehabilitation

S Souto-Miranda, V Rocha, MA Mendes, P Simão… - Respiratory …, 2023 - Elsevier
Introduction Studies suggest that people with chronic obstructive pulmonary disease
(COPD) who are worse at baseline respond better to pulmonary rehabilitation (PR) …

Demystification of artificial intelligence for respiratory clinicians managing patients with obstructive lung diseases

J Antão, J de Mast, A Marques… - Expert Review of …, 2023 - Taylor & Francis
Introduction Asthma and chronic obstructive pulmonary disease (COPD) are leading causes
of morbidity and mortality worldwide. Despite all available diagnostics and treatments, these …

Acute exacerbation prediction of COPD based on Auto-metric graph neural network with inspiratory and expiratory chest CT images

S Wang, W Li, N Zeng, J Xu, Y Yang, X Deng, Z Chen… - Heliyon, 2024 - cell.com
Chronic obstructive pulmonary disease (COPD) is a widely prevalent disease with
significant mortality and disability rates and has become the third leading cause of death …

Clustering of COPD patients and their response to pulmonary rehabilitation

Y Al Chikhanie, S Bailly, I Amroussa, D Veale… - Respiratory …, 2022 - Elsevier
Background and objective Pulmonary rehabilitation (PR) is fundamental in the management
of chronic obstructive pulmonary disease (COPD). COPD patients show a large clinical …