In recent years, spiro compounds have attracted significant interest in medicinal chemistry
due to their numerous biological activities attributed primarily to their versatility and structural …

Liver injury is a common pathological process characterized by massive degeneration and
abnormal death of liver cells. With increase in dead cells and necrosis, liver injury eventually …

This study identified koenidine (4) as a metabolically stable antidiabetic compound, when
evaluated in a rodent type 2 model (leptin receptor-deficient db/db mice), and showed a …

We have developed an efficient and mild enantioselective palladium-catalyzed (5+ 3)
cycloaddition of vinylcyclopropanes and oxidopyrylium ylides generated in situ from …

Heilaohu, the roots of Kadsura coccinea, has a long history of use in Tujia ethnomedicine for
the treatment of rheumatoid arthritis and gastroenteric disorders, and a lot of work has been …

Phytochemical investigations on the fresh fruits of Kadsura coccinea (Lem.) AC Sm. have led
to the isolation of fourteen undescribed 2, 2′-cyclolignans named heilaohuguosus AN, four …

Oxidative cyclizations create many unique chemical structures that are characteristic of
biologically active natural products. Many of these reactions are catalysed by 'non …

In China, the plants of genus Kadsura had been used as the folk medicines for a long time
and showed good effect of activating blood and dissolving stasis, promoting qi circulation to …

A dirhodium (II)‐catalyzed annulation reaction between two structurally different
diazocarbonyl compounds furnishes the donor–acceptor cyclopropane‐fused benzoxa [3.2 …

Ni-Catalyzed Ketene Cycloaddition: A System That Resists the Formation of Decarbonylation
Side Products | Journal of the American Chemical Society ACS ACS Publications C&EN CAS …