[HTML][HTML] Overview of the epidemiology, microbiology, and pathogenesis of Leptospira spp. in humans

R Plank, D Dean - Microbes and infection, 2000 - Elsevier
Leptospirosis is probably the world′ s most widespread zoonosis. It remains
underdiagnosed largely due to the broad spectrum of signs and symptoms attributable to …

Pathology and pathophysiology of pulmonary manifestations in leptospirosis

M Dolhnikoff, T Mauad, EP Bethlem… - Brazilian Journal of …, 2007 - SciELO Brasil
Leptospirosis is a re-emerging zoonosis occurring as large outbreaks throughout the world
caused by Leptospira interrogans. The incidence of pulmonary involvement in leptospirosis …

The cytolytically inactive terminal complement complex activates endothelial cells to express adhesion molecules and tissue factor procoagulant activity

F Tedesco, M Pausa, E Nardon, M Introna… - The Journal of …, 1997 - rupress.org
The membrane attack complex of complement (C) in sublytic concentrations stimulates
endothelial cells (EC) to express adhesion molecules and to release biologically active …

Duration of immunity in dogs vaccinated against leptospirosis with a bivalent inactivated vaccine

H Klaasen, M Molkenboer, MP Vrijenhoek… - Veterinary …, 2003 - Elsevier
Duration of immunity in dogs induced with current commercial inactivated leptospirosis
vaccines and evaluated against experimental infection, to date, has hardly been …

A Review on Host-Leptospira Interactions: What We Know and Future Expectations

BB Daroz, LGV Fernandes, MF Cavenague… - Frontiers in cellular …, 2021 - frontiersin.org
Leptospirosis is a widespread zoonosis caused by pathogenic Leptospira spp. It is
considered a neglected infectious disease of human and veterinary concern. Our group has …

Cytotoxic Activities of Leptospira interrogans Hemolysin SphH as a Pore-Forming Protein on Mammalian Cells

SH Lee, S Kim, SC Park, MJ Kim - Infection and immunity, 2002 - Am Soc Microbiol
Leptospirosis is a spirochetal zoonosis that causes an acute febrile systemic illness in
humans. Leptospira sp. hemolysins have been shown to be virulence factors for the …

Identification and partial characterization of a novel hemolysin from Leptospira interrogans serovar lai

SH Lee, KA Kim, YG Park, IW Seong, MJ Kim, YJ Lee - Gene, 2000 - Elsevier
It has been suggested that leptospiral hemolysins are important in the virulence and
pathogenesis of leptospirosis. We have isolated an Escherichia coli clone carrying the 7.8 …

Identification of Leptospira Species in the Pathogenesis of Uveitis and Determination of Clinical Ocular Characteristics in South India

KM Chu, R Rathinam… - The Journal of …, 1998 - academic.oup.com
Uveitis is considered a rare complication of leptospirosis. This report describes an epidemic
of uveitis among patients with leptospirosis and provides data, using polymerase chain …

[HTML][HTML] Clinicopathological and immunohistochemical featuresof the severe pulmonary form of leptospirosis

JJP Silva, MO Dalston, JEM Carvalho… - Revista da Sociedade …, 2002 - SciELO Brasil
Four cases of severe pulmonary form of leptospirosis (SPFL) are described. In all four of
these blood culture proven cases, there was severe pulmonary injury characterized by …

Leptospira interrogans activation of human peripheral blood mononuclear cells: preferential expansion of TCRγδ+ T cells vs TCRαβ+ T cells

GR Klimpel, MA Matthias, JM Vinetz - The Journal of Immunology, 2003 - journals.aai.org
Innate and adaptive immune responses induced by leptospirosis have not been well
characterized. In this study we show that in vitro exposure of naive human PBMC to …