Applications for transition-metal chemistry in contrast-enhanced magnetic resonance imaging

A Gupta, P Caravan, WS Price… - Inorganic …, 2020 - ACS Publications
Contrast-enhanced magnetic resonance imaging (MRI) is an indispensable tool for
diagnostic medicine. However, safety concerns related to gadolinium in commercial MRI …

Bioimaging agents based on redox-active transition metal complexes

SS Xue, Y Pan, W Pan, S Liu, N Li, B Tang - Chemical Science, 2022 - pubs.rsc.org
Detecting the fluctuation and distribution of various bioactive species in biological systems is
of great importance in determining diseases at their early stages. Metal complex-based …

19F MRI Probes for Multimodal Imaging**

D Janasik, T Krawczyk - Chemistry–A European Journal, 2022 - Wiley Online Library
Magnetic resonance imaging (MRI) is one of the most powerful imaging tools today, capable
of displaying superior soft‐tissue contrast. This review discusses developments in the field of …

Activatable Probes for Ratiometric Imaging of Endogenous Biomarkers In Vivo

Q Fu, X Yang, M Wang, K Zhu, Y Wang, J Song - ACS nano, 2024 - ACS Publications
Dynamic variations in the concentration and abnormal distribution of endogenous
biomarkers are strongly associated with multiple physiological and pathological states …

Fluorinated paramagnetic complexes: sensitive and responsive probes for magnetic resonance spectroscopy and imaging

KL Peterson, K Srivastava, VC Pierre - Frontiers in chemistry, 2018 - frontiersin.org
Fluorine magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI)
of chemical and physiological processes is becoming more widespread. The strength of this …

Redox-Responsive MRI Probes Based on First-Row Transition-Metal Complexes

JR Morrow, JJ Raymond, MSI Chowdhury… - Inorganic …, 2022 - ACS Publications
The presence of multiple oxidation and spin states of first-row transition-metal complexes
facilitates the development of switchable MRI probes. Redox-responsive probes capitalize …

Simultaneously activating highly selective ratiometric MRI and synergistic therapy in response to intratumoral oxidability and acidity

Y Liu, Q Jia, Q Guo, W Wei, J Zhou - Biomaterials, 2018 - Elsevier
Low selectivity is a major problem for cancer theranostics that has promoted the
development of molecularly-responsive nanomaterials. Herein, we report a novel …

Comparative paraCEST effect of amide and hydroxy groups in divalent cobalt and nickel complexes of tripyridine-based ligands

SK Panda, J Torres, C Kremer, AK Singh - Dalton Transactions, 2023 - pubs.rsc.org
Co (II) and Ni (II) complexes of two tri-pyridine-based ligands with two hydroxy and two
amide exchangeable protons (TDTA) and with six amide exchangeable protons (TMTP) …

Multiresponsive Nanoprobes for Turn-On Fluorescence/19F MRI Dual-Modal Imaging

Y Li, H Zhang, C Guo, G Hu, L Wang - Analytical Chemistry, 2020 - ACS Publications
Multiresponsive nanoprobes are highly desirable for low background and highly sensitive
imaging in biomedical applications. Herein, we design a glutathione (GSH)/pH dual …

An Fe complex for 19 F magnetic resonance-based reversible redox sensing and multicolor imaging

RT Kadakia, RT Ryan, DJ Cooke, EL Que - Chemical Science, 2023 - pubs.rsc.org
We report a first-in-class responsive, pentafluorosulfanyl (–SF5)-tagged 19F MRI agent
capable of reversibly detecting reducing environments via an FeII/III redox couple. In the …