The prognostication of colorectal cancer (CRC) has traditionally relied on staging as defined
by the Union for International Cancer Control (UICC) and American Joint Committee on …

Atomic force microscopy (AFM) allows for nanometer-scale investigation of cells and
molecules. Recent advances have enabled its application in cancer research and diagnosis …

Colorectal cancer (CRC) is a disease with complex pathogenesis, it is prone to metastasis,
and its development involves abnormalities in multiple signaling pathways. Surgery …

Over recent decades we have witnessed a shift in the anatomical distribution of gastric
cancer (GC), which increasingly originates from the proximal stomach near the junction with …

Abstract Background Circular RNAs (circRNAs) play a critical role in colorectal cancer
(CRC) progression, including metastasis. However, the detailed molecular mechanism is not …

The aryl hydrocarbon receptor (AHR) is an environmental sensor that integrates microbial
and dietary cues to influence physiological processes within the intestinal …

The EPH/ephrin system constitutes a bidirectional signaling pathway comprised of a family
of tyrosine kinase receptors in tandem with their plasma membrane-bound ligand (ephrins) …

Aberrant silencing of genes by DNA methylation contributes to cancer, yet how this process
is initiated remains unclear. Using a murine model of inflammation-induced tumorigenesis …

Cancer driver genes, ie, oncogenes and tumor suppressor genes, are involved in the
acquisition of important functions in tumors, providing a selective growth advantage …

The intestine-specific transcription factor Cdx2 is essential for intestinal homeostasis and
has been implicated in the pathogenesis of disorders including inflammatory bowel disease …