Scleral structure and biomechanics
As the eye's main load-bearing connective tissue, the sclera is centrally important to vision.
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
In addition to cooperatively maintaining refractive status with the cornea, the sclera must …
Biomechanics of the optic nerve head
Biomechanical factors acting at the level of the lamina cribrosa (LC) are postulated to play a
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
role in retinal ganglion cell dysfunction and loss in glaucoma. In support of this postulate, we …
Glaucomatous cupping of the lamina cribrosa: a review of the evidence for active progressive remodeling as a mechanism
The purpose of this review is to examine the literature in an attempt to elucidate a
biomechanical basis for glaucomatous cupping. In particular, this work focuses on the role of …
biomechanical basis for glaucomatous cupping. In particular, this work focuses on the role of …
[HTML][HTML] Spectral domain optical coherence tomography for glaucoma (an AOS thesis)
JS Schuman - Transactions of the American Ophthalmological …, 2008 - ncbi.nlm.nih.gov
Purpose Optical coherence tomography (OCT) is a rapidly evolving, robust technology that
has profoundly changed the practice of ophthalmology. Spectral domain OCT (SD-OCT) …
has profoundly changed the practice of ophthalmology. Spectral domain OCT (SD-OCT) …
Mechanical environment of the optic nerve head in glaucoma
JC Downs, MD Roberts… - Optometry and Vision …, 2008 - journals.lww.com
The optic nerve head (ONH) is of particular interest from a biomechanical perspective
because it is a weak spot within an otherwise strong corneo-scleral envelope. The lamina …
because it is a weak spot within an otherwise strong corneo-scleral envelope. The lamina …
Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma
RE Norman, JG Flanagan, IA Sigal, SMK Rausch… - Experimental eye …, 2011 - Elsevier
Scleral thickness, especially near the optic nerve head (ONH), is a potential factor of interest
in the development of glaucomatous optic neuropathy. Large differences in the dimensions …
in the development of glaucomatous optic neuropathy. Large differences in the dimensions …
Optic nerve head biomechanics in aging and disease
JC Downs - Experimental eye research, 2015 - Elsevier
This nontechnical review is focused upon educating the reader on optic nerve head
biomechanics in both aging and disease along two main themes: what is known about how …
biomechanics in both aging and disease along two main themes: what is known about how …
Laminar and prelaminar tissue displacement during intraocular pressure elevation in glaucoma patients and healthy controls
Y Agoumi, GP Sharpe, DM Hutchison, MT Nicolela… - Ophthalmology, 2011 - Elsevier
OBJECTIVE: To determine the response of the anterior lamina cribrosa and prelaminar
tissue to acute elevation of intraocular pressure (IOP) in glaucoma patients and healthy …
tissue to acute elevation of intraocular pressure (IOP) in glaucoma patients and healthy …
In vivo evaluation of focal lamina cribrosa defects in glaucoma
S Kiumehr, SC Park, S Dorairaj, CC Teng… - Archives of …, 2012 - jamanetwork.com
Objectives To assess focal lamina cribrosa (LC) defects in glaucoma using enhanced depth
imaging optical coherence tomography and to investigate their spatial relationships with …
imaging optical coherence tomography and to investigate their spatial relationships with …
Mechanosensitive release of adenosine 5′‐triphosphate through pannexin channels and mechanosensitive upregulation of pannexin channels in optic nerve head …
As adenosine 5′‐triphosphate (ATP) released from astrocytes can modulate many neural
signaling systems, the triggers and pathways for this ATP release are important. Here, the …
signaling systems, the triggers and pathways for this ATP release are important. Here, the …