Actin is among the most abundant proteins in eukaryotic cells and assembles into dynamic
filamentous networks regulated by many actin binding proteins. The actin cytoskeleton must …

Actin is one of the most abundant proteins in eukaryotic cells and the main component of the
microfilament system. It plays essential roles in numerous cellular activities, including …

Cellular form and function are controlled by the assembly and stability of actin cytoskeletal
structures—but disassembling/pruning these structures is equally essential for the plasticity …

Cellular events require the spatiotemporal interplay between actin assembly and actin
disassembly. Yet, how different factors promote the integration of these two opposing …

Actin and its dynamic structural remodelings are involved in multiple cellular functions,
including maintaining cell shape and integrity, cytokinesis, motility, navigation, and muscle …

Actin is one of the most abundant and essential intracellular proteins that mediates nearly
every form of cellular movement and underlies such key processes as embryogenesis …

Oxidant stress can contribute to health and disease. Here we show that invertebrates and
vertebrates share a common stereospecific redox pathway that protects against pathological …

MICAL1 has been reported to be involved in the malignant processes of several types of
cancer cells, however, the roles of MICAL1 in colorectal cancer (CRC) have not been well …

The F-actin cytoskeleton drives cellular form and function. However, how F-actin-based
changes occur with spatiotemporal precision and specific directional orientation is poorly …

Cellular form and function–and thus normal development and physiology–are specified via
proteins that control the organization and dynamic properties of the actin cytoskeleton. Using …