Understanding the role of key amino acids in regulation of proline dehydrogenase/proline oxidase (prodh/pox)-dependent apoptosis/autophagy as an approach to …

TYL Huynh, I Zareba, W Baszanowska… - Molecular and cellular …, 2020 - Springer
In stress conditions, as neoplastic transformation, amino acids serve not only as nutrients to
maintain the cell survival but also as mediators of several regulatory pathways which are …

Current and emerging biomarkers of cell death in human disease

K Li, D Wu, X Chen, T Zhang, L Zhang… - BioMed research …, 2014 - Wiley Online Library
Cell death is a critical biological process, serving many important functions within
multicellular organisms. Aberrations in cell death can contribute to the pathology of human …

Machine learning applied to whole‐blood RNA‐sequencing data uncovers distinct subsets of patients with systemic lupus erythematosus

WA Figgett, K Monaghan, M Ng… - Clinical & …, 2019 - Wiley Online Library
Objectives Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disease
that is difficult to treat. There is currently no optimal stratification of patients with SLE, and …

Analysis of the regulatory function of natural killer cells from patients with systemic lupus erythematosus

DJ Cruz-González, D Gómez-Martin… - Clinical & …, 2018 - academic.oup.com
Natural killer (NK) cells participate in the regulation of the immune response. However, the
immunomodulatory function of NK cells in systemic lupus erythematosus (SLE) is not well …

Reduced expressions of apoptosis-related proteins TRAIL, Bcl-2, and TNFR1 in NK cells of juvenile-onset systemic lupus erythematosus patients: relations with …

BL Liphaus, SC Silva, P Palmeira, CA Silva… - Frontiers in …, 2024 - frontiersin.org
Background Lupus pathogenesis is mainly ascribed to increased production and/or
impaired clearance of dead cell debris. Although self-reactive T and B lymphocytes are …

Neuroprotective effect of (‑)‑epigallocatechin‑3‑gallate on autoimmune thyroiditis in a rat model by an anti‑inflammation effect, anti‑apoptosis and inhibition of TRAIL …

J Li - Experimental and Therapeutic Medicine, 2018 - spandidos-publications.com
Epigallocatechin‑3‑gallate (EGCG) is a polyphenol monomer compound extracted and
separated from green tea, and is a key catechin in green tea. Recent research has identified …

Tumour necrosis factor-related apoptosis-inducing ligand expression in patients with diabetic nephropathy

W Chang, W Liang, X Yao, L Zhang… - Journal of the Renin …, 2018 - journals.sagepub.com
Objective: The objective of this study was to evaluate the expression profile of tumour
necrosis factor-related apoptosis-inducing ligand (TRAIL) in patients with diabetic …

[HTML][HTML] Assessment of tumor necrosis factor superfamily member 10 (TNFSF10) gene variants in systemic lupus erythematosus patients

A Kamal, RA Ibrahim, NMA Baki, MM Kamal - The Egyptian …, 2023 - Elsevier
Aim of the work To investigate the association between tumor necrosis factor (TNF) related
apoptosis-inducing ligand (TRAIL) 1525 G> A (TNF supefamily member 10; TNFSF10 …

[HTML][HTML] Patterns of microRNAs 142-3p, 106a, 17 and 20a expression in patients with systemic lupus erythematosus

HG AlDeen, A Ramadan, E Awadallah… - The Egyptian …, 2022 - Elsevier
Introduction Systemic lupus erythematosus (SLE) is a connective tissue disorder which
involves immune system dysregulation. Micro-ribonucleic acids (MiRNAs) up and down …

[HTML][HTML] Apoptosis of Dendritic Cells and Autoimmune Disease

L Sun, F Ding, L Zhou, J Wang, M Li, P Zhou… - Frontiers in Bioscience …, 2024 - imrpress.com
Dendritic cells (DCs), the most efficient antigen-presenting cells (APCs), bridge the innate
and adaptive immune systems. As such, the turn-over of DCs is critical during autoimmune …