The use of pigs in neuroscience research has increased in the past decade, which has seen
broader recognition of the potential of pigs as an animal for experimental modeling of …

In regulatory toxicology studies, qualitative histopathological evaluation is the reference
standard for assessment of test article–related morphological changes. In certain cases …

The pig model is increasingly used in the field of neuroscience because of the similarities of
its brain with human. This review presents the peculiarities of the anatomy and functions of …

White matter (WM) fractional anisotropy (FA) is thought to be related to WM integrity and
decline in FA is often used as an index of decreasing WM health. However, the relationship …

An animal model with brain growth similar to humans, that can be used in MRI studies to
investigate brain development, would be valuable. Our laboratory has developed and …

We explored relationships between decline in cognitive processing speed (CPS) and
change in frontal lobe MRI/MRS-based indices of cerebral integrity in 38 healthy adults (age …

Leftward volume asymmetry of the pars opercularis and pars triangularis may exist in the
human brain, frequently referred to as Broca's area, given the functional asymmetries …

Freely available automated MR image analysis techniques are being increasingly used to
investigate neuroanatomical abnormalities in patients with neurological disorders. It is …

Background Human central nervous system-stem cells grown as neurospheres (hCNS-
SCns) self-renew, are multipotent, and have potential therapeutic applications following …

Age-related brain changes are widely documented. Because of differences in measurement
methods and case selection, the reported effects of age on regional grey and white matter …