The role of exosomes and exosomal noncoding RNAs from different cell sources in spinal cord injury

ZL Yang, J Rao, FB Lin, ZY Liang, XJ Xu… - Frontiers in Cellular …, 2022 - frontiersin.org
Spinal cord injury (SCI) not only affects the quality of life of patients but also poses a heavy
burden on their families. Therefore, it is essential to prevent the occurrence of SCI; for …

Bone mesenchymal stem cell-derived extracellular vesicles deliver microRNA-23b to alleviate spinal cord injury by targeting toll-like receptor TLR4 and inhibiting NF …

H Nie, Z Jiang - Bioengineered, 2021 - Taylor & Francis
Bone mesenchymal stem cell-derived extracellular vesicles (BMSC-EVs) are known for
recovery of injured tissues. We investigated the possible mechanism of BMSC-EVs in spinal …

MicroRNA-211/BDNF axis regulates LPS-induced proliferation of normal human astrocyte through PI3K/AKT pathway

K Zhang, S Wu, Z Li, J Zhou - Bioscience reports, 2017 - portlandpress.com
Spinal cord injury (SCI) makes a major contribution to disability and deaths worldwide.
Reactive astrogliosis, a typical feature after SCI, which undergoes varying molecular and …

MiR-140/BDNF axis regulates normal human astrocyte proliferation and LPS-induced IL-6 and TNF-α secretion

Z Tu, Y Li, Y Dai, L Li, G Lv, I Chen, B Wang - Biomedicine & …, 2017 - Elsevier
Reactive astrocyte proliferation after spinal cord injury (SCI) contributes to glial scar
formation that impedes axonal regeneration. The mechanisms underlying astrocyte …

The LncRNA H19/miR-1-3p/CCL2 axis modulates lipopolysaccharide (LPS) stimulation-induced normal human astrocyte proliferation and activation

P Li, Y Li, Y Dai, B Wang, L Li, B Jiang, P Wu, J Xu - Cytokine, 2020 - Elsevier
Reactive astrocyte proliferation post SCI (spinal cord injury) leads to the formation of glial
scars, thus hindering axon regeneration and SCI repair, during which the activation of …

MicroRNA-182 aggravates cerebral ischemia injury by targeting inhibitory member of the ASPP family (iASPP)

H Yi, Y Huang, F Yang, W Liu, S He, X Hu - Archives of Biochemistry and …, 2017 - Elsevier
Ischemic stroke is one of the leading causes of death and disability globally and has been
regarded as a major public health problem. MicroRNA 182 (miR-182) plays important roles …

The Role of Exosomes from Mesenchymal Stem Cells in Spinal Cord Injury: A Systematic Review

H Wang, C Zhao, Q Rong, J Cao, H Chen… - International Journal of …, 2023 - ijstemcell.com
Spinal cord injury (SCI) is a serious nervous system disease that usually leads to the
impairment of the motor, sensory, and autonomic nervous functions of the spinal cord, and it …

miR-194-5p inhibits LPS-induced astrocytes activation by directly targeting neurexophilin 1

M Wang, Z Li, Q Zuo - Molecular and Cellular Biochemistry, 2020 - Springer
Astrocytes are vitally involved in the development of neurodegenerative diseases and brain
cancers. In this work, we investigated the potential ameliorative role of microRNA-194-5p …

Pectolinarigenin promotes functional recovery and inhibits apoptosis in rats following spinal cord injuries

B Wu, J Liang - Experimental and Therapeutic …, 2019 - spandidos-publications.com
Spinal cord injury (SCI) is a devastating neurological injury that frequently leads to
neurological defects and disabilities. The only effective pharmacotherapy currently available …

[HTML][HTML] 急性颈脊髓损伤手术时机的研究进展

宋应豪, 孔祥宇, 席宇君, 曾光亮, 李如军… - International Journal of …, 2017 - hanspub.org
脊柱脊髓损伤是当前危害人类健康的常见病, 多发病, 其中以颈髓损伤最为多见.
急性颈髓损伤是一种很严重的创伤疾病, 具有高致残率, 致死率的特点. 近年来对急性颈脊髓损伤 …