The comet assay in animal models: From bugs to whales–(Part 1 Invertebrates)

G Gajski, B Žegura, C Ladeira, B Pourrut… - … Research/Reviews in …, 2019 - Elsevier
The comet assay, also called single cell gel electrophoresis, is a sensitive, rapid and low-
cost technique for quantifying and analysing DNA damage and repair at the level of …

Role of the immune system in regeneration and its dynamic interplay with adult stem cells

P Abnave, E Ghigo - Seminars in cell & developmental biology, 2019 - Elsevier
The immune system plays an indispensable role in the process of tissue regeneration
following damage as well as during homeostasis. Inflammation and immune cell recruitment …

Toxicity of metal oxide nanoparticles in immune cells of the sea urchin

C Falugi, MG Aluigi, MC Chiantore, D Privitera… - Marine Environmental …, 2012 - Elsevier
The potential toxicity of stannum dioxide (SnO2), cerium dioxide (CeO2) and iron oxide
(Fe3O4) nanoparticles (NPs) in the marine environment was investigated using the sea …

High-throughput comet assay using 96 minigels

KB Gutzkow, TM Langleite, S Meier, A Graupner… - …, 2013 - academic.oup.com
The single-cell gel electrophoresis—the comet assay—has proved to be a sensitive and
relatively simple method that is much used in research for the analysis of specific types of …

Stem cells and innate immunity in aquatic invertebrates: Bridging two seemingly disparate disciplines for new discoveries in biology

L Ballarin, A Karahan, A Salvetti, L Rossi… - Frontiers in …, 2021 - frontiersin.org
The scopes related to the interplay between stem cells and the immune system are broad
and range from the basic understanding of organism's physiology and ecology to …

The salamander blastema within the broader context of metazoan regeneration

B Tajer, AM Savage, JL Whited - Frontiers in Cell and Developmental …, 2023 - frontiersin.org
Throughout the animal kingdom regenerative ability varies greatly from species to species,
and even tissue to tissue within the same organism. The sheer diversity of structures and …

Echinodermata

MI Arnone, M Byrne, P Martinez - Evolutionary developmental biology of …, 2015 - Springer
Echinoderms are a phylum of invertebrate deuterostomes that are morphologically
characterized by a fivefold (pentameric) symmetric adult body plan. There are five extant …

Beyond adult stem cells: dedifferentiation as a unifying mechanism underlying regeneration in invertebrate deuterostomes

C Ferrario, M Sugni, IML Somorjai… - Frontiers in Cell and …, 2020 - frontiersin.org
The diversity of regenerative phenomena seen in adult metazoans, as well as their
underlying mechanistic bases, are still far from being comprehensively understood …

Transcriptomic analysis of early stages of intestinal regeneration in Holothuria glaberrima

DJ Quispe-Parra, JG Medina-Feliciano… - Scientific Reports, 2021 - nature.com
Echinoderms comprise a group of animals with impressive regenerative capabilities. They
can replace complex internal organs following injury or autotomy. In holothurians or sea …

Analysis of sea star larval regeneration reveals conserved processes of whole-body regeneration across the metazoa

GA Cary, A Wolff, O Zueva, J Pattinato, VF Hinman - BMC biology, 2019 - Springer
Background Metazoan lineages exhibit a wide range of regenerative capabilities that vary
among developmental stage and tissue type. The most robust regenerative abilities are …