1H and 31P MR Spectroscopy to Assess Muscle Mitochondrial Dysfunction in Long COVID

LEM Finnigan, MP Cassar, M Jafarpour, A Sultana… - Radiology, 2024 - pubs.rsna.org
Background Emerging evidence suggests mitochondrial dysfunction may play a role in the
fatigue experienced by individuals with post–COVID-19 condition (PCC), commonly called …

Correlation between skeletal muscle acetylcarnitine and phosphocreatine metabolism during submaximal exercise and recovery: interleaved 1H/31P MRS 7 T study

R Klepochová, F Niess, M Meyerspeer, D Slukova… - Scientific Reports, 2024 - nature.com
Acetylcarnitine is an essential metabolite for maintaining metabolic flexibility and glucose
homeostasis. The in vivo behavior of muscle acetylcarnitine content during exercise has not …

Maternal metabolites associated with gestational diabetes mellitus and a postpartum disorder of glucose metabolism

Y Liu, A Kuang, JR Bain, MJ Muehlbauer… - The Journal of …, 2021 - academic.oup.com
Context Gestational diabetes is associated with a long-term risk of developing a disorder of
glucose metabolism. However, neither the metabolic changes characteristic of gestational …

Postcontraction [acetylcarnitine] reflects interindividual variation in skeletal muscle ATP production patterns in vivo

CMT Hayden, R Nagarajan, ZH Smith… - American Journal …, 2024 - journals.physiology.org
In addition to its role in substrate selection (carbohydrate vs. fat) for oxidative metabolism in
muscle, acetylcarnitine production may be an important modulator of the energetic pathway …

Pyrroloquinoline quinone attenuated benzyl butyl phthalate induced metabolic aberration and a hepatic metabolomic analysis

J Zhang, C Powell, S Meruvu, R Sonkar… - Biochemical …, 2022 - Elsevier
Benzyl butyl phthalate (BBP) has recently been implicated as an obesogen. Our recent study
demonstrated that BBP can exacerbate high fat diet (HFD) induced diabesity in male mice …

1H‐NMR‐based metabolomics reveals the preventive effect of Enteromorpha prolifera polysaccharides on diabetes in Zucker diabetic fatty rats

J Chen, S Wang, F Guo, Y Gong, T Chen… - Food Science & …, 2024 - Wiley Online Library
The primary objective of this investigation was to explore the beneficial impacts of
Enteromorpha prolifera polysaccharide (EP) on dysglycemia in Zucker diabetic fatty (ZDF) …

The effects of regular exercise on cognitive and cardiometabolic health in testicular cancer survivors subjected to platinum‐based chemotherapy

A Amiri, L Slobodová, R Klepochová, M Schön… - …, 2025 - Wiley Online Library
Background Platinum‐based chemotherapy provides curative treatment to more than 95% of
patients with testicular germ cell tumor but it has negative cardiometabolic and neurological …

Skeletal muscle fat

I Just, M Krššák - Visceral and Ectopic Fat, 2023 - Elsevier
Abstracts In his chapter the (patho) physiologic role of two distinct skeletal muscle depots,
intramuscular adipose tissue and intramyocellular lipids, is reviewed. Connections of …

Skeletal muscle acetylcarnitine during submaximal exercise and recovery: Interleaved H/31 P MRS 7T pilot study

R Klepochová, F Niess, M Meyerspeer, S Trattnig… - archive.ismrm.org
The study aimed to explore the behavior of skeletal muscle acetylcarnitine and
phosphocreatine during submaximal plantar flexion exercise using interleaved 1 H/31 P …