Background Evidence-based recommendations for treating persons having presumed latent
tuberculosis (LTBI) after contact to infectious multidrug-resistant (MDR) tuberculosis (TB) are …

ABSTRACT Multidrug‐resistant (MDR) tuberculosis (TB) denotes bacillary resistance to at
least isoniazid and rifampicin. Extensively drug‐resistant (XDR) TB is MDR‐TB with …

Tuberculosis (TB) is an ancient and deadly disease characterized by complex host-
pathogen dynamics playing out over multiple time and length scales and physiological …

Preventing the progression of a drug-resistant tuberculosis (DR-TB) infection to disease is
an important pillar of the DR-TB elimination strategy. International guidelines have recently …

Background. It is necessary to develop a safe alternative to isoniazid for tuberculosis
prophylaxis in liver transplant recipients. This study was designed to investigate the efficacy …

Latent tuberculosis infection (LTBI) refers to a circumstance in which viable Mycobacterium
tuberculosis (MTB) bacilli are present in an individual but symptoms and signs of active …

Rationale: Fluoroquinolone (FQN) therapy of latent tuberculosis infection among contacts of
individuals with multidrug-resistant tuberculosis (MDR-TB) is controversial. Objectives: To …

M ycobacterium tuberculosis, the causative agent of tuberculosis (TB), has developed
various mechanisms to survive and cause disease in the human host. Incomplete …

Background The cost of treating and managing cases of active tuberculosis (TB) disease—
from diagnosis to treatment completion—is needed by agencies working on public health …

Opinion statement The treatment of latent tuberculosis infection (LTBI) is an essential
component of tuberculosis (TB) elimination in regions that have a low incidence of TB …