Sortase A (SrtA) inhibitors as an alternative treatment for superbug infections

S Alharthi, SE Alavi, PM Moyle, ZM Ziora - Drug Discovery Today, 2021 - Elsevier
Virulence factor, sortase A (SrtA), has crucial roles in the pathogenesis of Gram-positive
superbugs. SrtA is a bacterial cell membrane enzyme that anchors crucial virulence factors …

Infection and burn injury

EJ Kelly, MA Oliver, BC Carney, JW Shupp - European Burn Journal, 2022 - mdpi.com
Burn injury is debilitating and among one of the most frequently occurring traumas. Critical
care improvements have allowed for increasingly positive outcomes. However, infection …

Distribution patterns and influential factors of pathogenic bacteria in freshwater aquaculture sediments

W Xi, X Zhang, X Zhu, J Wang, H Xue, H Pan - Environmental Science and …, 2024 - Springer
Pathogenic bacteria, the major causative agents of aquaculture diseases, are a serious
impediment to the aquaculture industry. However, the bioinformatics of pathogenic bacteria …

Repurposing farnesol for combating drug-resistant and persistent single and polymicrobial biofilms

L Tan, R Ma, T Reeves, AJ Katz, N Levi - Antibiotics, 2024 - mdpi.com
Biofilm-associated infections caused by drug-resistant and persistent bacteria remain a
significant clinical challenge. Here we report that farnesol, commercially available as a …

Stimuli-responsive nanoplatform-assisted photodynamic therapy against bacterial infections

Y Zhou, W Deng, M Mo, D Luo, H Liu, Y Jiang… - Frontiers in …, 2021 - frontiersin.org
Bacterial infections are common diseases causing tremendous deaths in clinical settings. It
has been a big challenge to human beings because of the antibiotics abuse and the newly …

[HTML][HTML] Screening of Toxin Genes in Methicillin-Resistant Staphylococcus aureus Clinical Isolates from a Hospital Setting in a Tertiary Hospital in Northern Cyprus

TMF Potindji, OAA Momani, BB Omowumi… - Polish Journal of …, 2022 - ncbi.nlm.nih.gov
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant opportunistic pathogen
with a wide repertoire of virulence characteristics. Data regarding the molecular profile of …

[HTML][HTML] Farnesol Emulsion as an Effective Broad-Spectrum Agent against ESKAPE Biofilms

L Tan, R Ma, AJ Katz, N Levi - Antibiotics, 2024 - mdpi.com
The family of ESKAPE pathogens is comprised of Enterococcus faecium, Staphylococcus
aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and …

Monomicrobial necrotizing fasciitis and sepsis caused by Pseudomonas aeruginosa and Pseudomonas fluorescens: a series of ten cases

JL Chen, TY Huang, LT Kuo, KC Huang… - Japanese Journal of …, 2022 - jstage.jst.go.jp
抄録 Monomicrobial necrotizing fasciitis caused by Pseudomonas species is a rare infection.
This study aimed to elucidate the specific characteristics and clinical outcomes of necrotizing …

Isolation and characterization of bacteriophages from sewerage water targeting methicillin resistance S. aureus in burn patients

N Zafar, A Aslam, SU Rahman, M Saqib - 2024 - researchsquare.com
The spectrum of infections caused by methicillin-resistant Staphylococcus aureus (MRSA)
ranges from minor to potentially life-threatening. Due to its increased antibiotic resistance …

Screening of Toxin Genes in Methicillin-Resistant Clinical Isolates from a Hospital Setting in a Tertiary Hospital in Northern Cyprus

TMF Potindji, OAA Momani, BB Omowumi… - Polish Journal of … - sciendo.com
Methicillin-resistant Staphylococcus aureus (MRSA) is a significant opportunistic pathogen
with a wide repertoire of virulence characteristics. Data regarding the molecular profile of …