[HTML][HTML] Advances and trends in omics technology development

X Dai, L Shen - Frontiers in Medicine, 2022 - frontiersin.org
The human history has witnessed the rapid development of technologies such as high-
throughput sequencing and mass spectrometry that led to the concept of 'omics' and …

[HTML][HTML] The crucial role of protein phosphorylation in cell signaling and its use as targeted therapy

F Ardito, M Giuliani, D Perrone… - International …, 2017 - spandidos-publications.com
Protein phosphorylation is an important cellular regulatory mechanism as many enzymes
and receptors are activated/deactivated by phosphorylation and dephosphorylation events …

[HTML][HTML] Translational precision medicine: an industry perspective

D Hartl, V de Luca, A Kostikova, J Laramie… - Journal of translational …, 2021 - Springer
In the era of precision medicine, digital technologies and artificial intelligence, drug
discovery and development face unprecedented opportunities for product and business …

[图书][B] Radiobiology for the Radiologist

EJ Hall, AJ Giaccia - 2006 - redjournal.org
Many refer to the textbook Radiobiology for the Radiologist as the “bible” of radiation biology
for educating residents, researchers, and clinicians. Dr. Eric Hall has compiled, written, and …

[PDF][PDF] 'Omic'technologies: genomics, transcriptomics, proteomics and metabolomics.

RP Horgan, LC Kenny - Obstetrician & Gynaecologist, 2011 - researchgate.net
'Omic'technologies adopt a holistic view of the molecules that make up a cell, tissue or
organism. They are aimed primarily at the universal detection of genes (genomics), mRNA …

[HTML][HTML] Protein immobilization techniques for microfluidic assays

D Kim, AE Herr - Biomicrofluidics, 2013 - pubs.aip.org
Microfluidic systems have shown unequivocal performance improvements over conventional
bench-top assays across a range of performance metrics. For example, specific advances …

Protein biomarker discovery and validation: the long and uncertain path to clinical utility

N Rifai, MA Gillette, SA Carr - Nature biotechnology, 2006 - nature.com
Better biomarkers are urgently needed to improve diagnosis, guide molecularly targeted
therapy and monitor activity and therapeutic response across a wide spectrum of disease …

Biomarkers in cancer staging, prognosis and treatment selection

JA Ludwig, JN Weinstein - Nature Reviews Cancer, 2005 - nature.com
Advances in genomics, proteomics and molecular pathology have generated many
candidate biomarkers with potential clinical value. Their use for cancer staging and …

Nanotechnology applications in cancer

S Nie, Y Xing, GJ Kim, JW Simons - Annu. Rev. Biomed. Eng., 2007 - annualreviews.org
Cancer nanotechnology is an interdisciplinary area of research in science, engineering, and
medicine with broad applications for molecular imaging, molecular diagnosis, and targeted …

From genomics to proteomics

M Tyers, M Mann - Nature, 2003 - nature.com
Proteomics is the study of the function of all expressed proteins. Tremendous progress has
been made in the past few years in generating large-scale data sets for protein–protein …