Regulation and dysregulation of Epstein–Barr virus latency: implications for the development of autoimmune diseases

HH Niller, H Wolf, J Minarovits - Autoimmunity, 2008 - Taylor & Francis
Epstein–Barr virus (EBV) is a human herpesvirus hiding in a latent form in memory B cells in
the majority of the world population. Although, primary EBV infection is asymptomatic or …

Shaping immunity: The influence of natural selection on population immune diversity

HE Randolph, KA Aracena, YL Lin, Z Mu… - Immunological …, 2024 - Wiley Online Library
Humans exhibit considerable variability in their immune responses to the same immune
challenges. Such variation is widespread and affects individual and population‐level …

Epstein–Barr virus and rheumatoid arthritis: is there a link?

KH Costenbader, EW Karlson - Arthritis research & therapy, 2006 - Springer
Rheumatoid arthritis is a systemic autoimmune disease characterized by chronic,
destructive, debilitating arthritis. Its etiology is unknown; it is presumed that environmental …

Aberrant Epstein–Barr viral infection in systemic lupus erythematosus

BD Poole, AK Templeton, JM Guthridge, EJ Brown… - Autoimmunity …, 2009 - Elsevier
Serologic association, cross-reactivity of select EBV-specific antibodies with SLE
autoantigens, SLE-like autoimmunity after immunization with EBV peptides, increased EB …

Analysis of the saliva metabolic signature in patients with primary Sjögren's syndrome

Z Li, Y Mu, C Guo, X You, X Liu, Q Li, W Sun - PLoS One, 2022 - journals.plos.org
Background The saliva metabolome has been applied to explore disease biomarkers. In this
study we characterized the metabolic profile of primary Sjögren's syndrome (pSS) patients …

Innate immunity in Sjögren's syndrome

J Kiripolsky, LG McCabe, JM Kramer - Clinical immunology, 2017 - Elsevier
Sjögren's syndrome (SS) is an autoimmune disease of exocrine tissue that primarily affects
women. Although patients typically experience xerostomia and xerophthalmia, numerous …

A glimpse into the microbiome of Sjögren's syndrome

C Deng, Q Xiao, Y Fei - Frontiers in Immunology, 2022 - frontiersin.org
Sjögren's syndrome (SS) is a common chronic systemic autoimmune disease and its main
characteristic is lymphoid infiltration of the exocrine glands, particularly the salivary and …

The contribution of natural selection to present-day susceptibility to chronic inflammatory and autoimmune disease

JF Brinkworth, LB Barreiro - Current opinion in immunology, 2014 - Elsevier
Highlights•GWAS suggest pathological inflammation is controlled by a small network of
genes.•Many chronic inflammatory/autoimmune risk alleles occur in regions of positive …

Epstein–Barr virus and systemic lupus erythematosus

JA James, JB Harley, RH Scofield - Current opinion in …, 2006 - journals.lww.com
This review will briefly outline the recent advances that show serologic, DNA, gene
expression, viral load, T cell responses, humoral fine specificity, and molecular mimicry …

Xerostomia secondary to Sjögren's syndrome in the elderly: recognition and management

I Al-Hashimi - Drugs & aging, 2005 - Springer
Xerostomia is a common symptom in the elderly population. Studies have suggested that the
underlying cause of approximately 40% of xerostomia in the elderly is Sjögren's syndrome …