Background. The efficacy of tenofovir disoproxil fumarate (TDF) as part of combination
antiretroviral treatment (ART) has been demonstrated in several randomized, controlled …

Almost 20 years after the broad antiviral activity spectrum of the first acyclic nucleoside
phosphonates was described, several of these compounds have become important …

It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Objective: Despite widespread HAART use, HIV disease remains associated with increased
risk of kidney disease. Whether tenofovir use is associated with higher risk of kidney disease …

ContextTenofovir disoproxil fumarate (DF) is a once-daily nucleotide analogue reverse
transcriptase inhibitor. ObjectiveTo evaluate the efficacy and safety of tenofovir DF …

Medications are a common cause of AKI, especially for patients admitted to hospital wards
and the intensive care unit. Although drug-related kidney injury occurs through different …

Background Durable suppression of replication of the human immunodeficiency virus (HIV)
depends on the use of potent, well-tolerated antiretroviral regimens to which patients can …

Objectives: Chronic kidney disease (CKD) in HIV-positive persons might be caused by both
HIV and traditional or non-HIV-related factors. Our objective was to investigate long-term …

Tenofovir (TDF) is an effective and widely used treatment for both human immunodeficiency
virus (HIV) and hepatitis B virus infection. Although studies suggest that TDF has a low …

Abstract Background. Several antiretroviral agents (ARVs) are associated with chronic renal
impairment, but the extent of such adverse events among human immunodeficiency virus …