IgG replacement in multiple myeloma

A Wonnaparhown, T Hilal, J Squire, C Freeman… - Blood cancer …, 2024 - nature.com
T cell engagers (TCE) such as chimeric antigen receptor (CAR) T cell therapy and bispecific
antibodies (BiAbs) for the treatment of multiple myeloma (MM) have significantly improved …

A safety review of recently approved and emerging drugs for patients with relapsed or refractory multiple myeloma

S Midha, MA Hartley-Brown, CC Mo… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Multiple new drugs have been approved over the past 5 years for the treatment
of relapsed/refractory multiple myeloma (RRMM), and these are being increasingly widely …

Outcomes of COVID‐19 in multiple myeloma patients treated with daratumumab

D Jin, J He, W Wu, X Han, J Le, W Shu, J Fu… - Cancer …, 2024 - Wiley Online Library
Despite concerns about an increased risk of adverse outcomes following coronavirus
disease (COVID‐19) in multiple myeloma patients treated with anti‐CD38 Abs, the impact of …

Efficacy and safety of daratumumab with ixazomib and dexamethasone in lenalidomide‐exposed patients after one prior line of therapy: final results of the phase 2 …

E Terpos, I Ntanasis‐Stathopoulos… - American Journal of …, 2024 - Wiley Online Library
The use of lenalidomide in frontline therapy for patients with newly diagnosed multiple
myeloma (MM) has increased the number of those who become refractory to lenalidomide at …

Reporting of adverse events of treatment interventions in multiple myeloma: an overview of systematic reviews

M Mainou, KI Bougioukas, K Malandris, A Liakos… - Annals of …, 2024 - Springer
The present study is an overview of systematic reviews focusing on adverse events of
antimyeloma treatments. It provides a systematic description of adverse events as they are …

Belantamab mafodotin, lenalidomide and dexamethasone in transplant-ineligible patients with newly diagnosed multiple myeloma: part 1 results of a phase I/II study

E Terpos, M Gavriatopoulou… - …, 2024 - pmc.ncbi.nlm.nih.gov
Preclinical and clinical data demonstrate synergy between belantamab mafodotin (belamaf)
and immunomodulatory drugs with limited overlapping toxicities. We investigated the safety …

Infections in patients with mantle cell lymphoma

KD Abalo, S Ekberg, TML Andersson, S Pahnke… - …, 2024 - Wiley Online Library
Advancements in treatments have significantly improved the prognosis for mantle cell
lymphoma (MCL), and there is a growing population of survivors with an increased …

[HTML][HTML] Immunoglobulin Replacement Therapy: Insights into Multiple Myeloma Management

I Saltarella, C Altamura, AG Solimando, S D'Amore… - Cancers, 2024 - mdpi.com
Simple Summary Immunoglobulin (Ig) replacement therapy (IgRT) consists of the
administration of low-doses human polyclonal Igs for the treatment of primary and secondary …

Hepatitis B reactivation in patients with multiple myeloma treated with anti-CD38 monoclonal antibody-based therapies: a pharmacovigilance analysis

DC Moore, JB Elmes, JR Arnall, SA Strassels… - International Journal of …, 2023 - Springer
Background Daratumumab and isatuximab are anti-CD38 monoclonal antibodies indicated
for the treatment of multiple myeloma. These agents can increase the risk of infectious …

The Challenging Approach to Multiple Myeloma: From Disease Diagnosis and Monitoring to Complications Management

S Morè, L Corvatta, VM Manieri, E Morsia, M Offidani - Cancers, 2024 - mdpi.com
Simple Summary Multiple myeloma (MM) represents the second most common
hematological malignancy, but its diagnosis can be significantly delayed since symptoms …