Drug delivery by supramolecular design

MJ Webber, R Langer - Chemical Society Reviews, 2017 - pubs.rsc.org
The rational design of drug delivery approaches leveraging supramolecular chemistry
(ie,“chemistry beyond the molecule”) has garnered significant interest in recent years toward …

Self-assembling peptide and protein amyloids: from structure to tailored function in nanotechnology

G Wei, Z Su, NP Reynolds, P Arosio… - Chemical Society …, 2017 - pubs.rsc.org
Self-assembled peptide and protein amyloid nanostructures have traditionally been
considered only as pathological aggregates implicated in human neurodegenerative …

Advances and perspectives in carrier-free nanodrugs for cancer chemo-monotherapy and combination therapy

L Huang, S Zhao, F Fang, T Xu, M Lan, J Zhang - Biomaterials, 2021 - Elsevier
Nanocarrier-based drug delivery systems hold impressive promise for biomedical
application because of their excellent water dispersibility, prolonged blood circulation time …

Drug self-delivery systems for cancer therapy

SY Qin, AQ Zhang, SX Cheng, L Rong, XZ Zhang - Biomaterials, 2017 - Elsevier
Carrier-assistant drug delivery systems (DDSs) have been rapidly established for cancer
therapy and great strides have been made in recent years. However, further development of …

Peptide–drug conjugates as effective prodrug strategies for targeted delivery

Y Wang, AG Cheetham, G Angacian, H Su, L Xie… - Advanced drug delivery …, 2017 - Elsevier
Peptide–drug conjugates (PDCs) represent an important class of therapeutic agents that
combine one or more drug molecules with a short peptide through a biodegradable linker …

Self-assembling prodrugs

AG Cheetham, RW Chakroun, W Ma… - Chemical Society Reviews, 2017 - pubs.rsc.org
Covalent modification of therapeutic compounds is a clinically proven strategy to devise
prodrugs with enhanced treatment efficacies. This prodrug strategy relies on the modified …

Research progress on self-assembled nanodrug delivery systems

L Qiao, H Yang, S Gao, L Li, X Fu, Q Wei - Journal of materials …, 2022 - pubs.rsc.org
In recent years, nanodrug delivery systems have attracted increasing attention due to their
advantages, such as high drug loading, low toxicity and side effects, improved …

Cationic surfactants: Self-assembly, structure-activity correlation and their biological applications

LY Zakharova, TN Pashirova, S Doktorovova… - … Journal of Molecular …, 2019 - mdpi.com
The development of biotechnological protocols based on cationic surfactants is a modern
trend focusing on the fabrication of antimicrobial and bioimaging agents, supramolecular …

Light-triggered, self-immolative nucleic acid-drug nanostructures

X Tan, BB Li, X Lu, F Jia, C Santori… - Journal of the …, 2015 - ACS Publications
The simultaneous intracellular delivery of multiple types of payloads, such as hydrophobic
drugs and nucleic acids, typically requires complex carrier systems. Herein, we demonstrate …

Peptide-based nanoprobes for molecular imaging and disease diagnostics

P Zhang, Y Cui, CF Anderson, C Zhang, Y Li… - Chemical Society …, 2018 - pubs.rsc.org
Pathological changes in a diseased site are often accompanied by abnormal activities of
various biomolecules in and around the involved cells. Identifying the location and …