[HTML][HTML] Advances in the early diagnosis of hepatocellular carcinoma

W Wang, C Wei - Genes & diseases, 2020 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most prevalent cancers globally. In contrast to
the declining death rates observed for all other common cancers such as breast, lung, and …

[HTML][HTML] Biomarkers for the early diagnosis of hepatocellular carcinoma

N Tsuchiya, Y Sawada, I Endo, K Saito… - World journal of …, 2015 - ncbi.nlm.nih.gov
Hepatocellular carcinoma (HCC) is the fifth most common cancer and the second leading
cause of cancer-related deaths worldwide. Although the prognosis of patients with HCC is …

The spatiotemporal program of zonal liver regeneration following acute injury

S Ben-Moshe, T Veg, R Manco, S Dan, D Papinutti… - Cell Stem Cell, 2022 - cell.com
The liver carries a remarkable ability to regenerate rapidly after acute zonal damage. Single-
cell approaches are necessary to study this process, given the spatial heterogeneity of liver …

Biomarkers for diagnosis and therapeutic options in hepatocellular carcinoma

YT Chan, C Zhang, J Wu, P Lu, L Xu, H Yuan, Y Feng… - Molecular Cancer, 2024 - Springer
Liver cancer is a global health challenge, causing a significant social-economic burden.
Hepatocellular carcinoma (HCC) is the predominant type of primary liver cancer, which is …

The threshold of alpha-fetoprotein (AFP) for the diagnosis of hepatocellular carcinoma: A systematic review and meta-analysis

J Zhang, G Chen, P Zhang, J Zhang, X Li, D Gan… - PloS one, 2020 - journals.plos.org
Objective Hepatocellular carcinoma (HCC) has become a pressing health problem facing
the world today due to its high morbidity, high mortality, and late discovery. As a diagnostic …

Osteopontin: a key regulator of tumor progression and immunomodulation

HR Moorman, D Poschel, JD Klement, C Lu, PS Redd… - Cancers, 2020 - mdpi.com
Simple Summary Anti-PD-1/PD-L1 and anti-CTLA-4-based immune checkpoint blockade
(ICB) immunotherapy have recently emerged as a breakthrough in human cancer treatment …

[HTML][HTML] DNA methylation-driven genes for constructing diagnostic, prognostic, and recurrence models for hepatocellular carcinoma

J Long, P Chen, J Lin, Y Bai, X Yang, J Bian, Y Lin… - Theranostics, 2019 - ncbi.nlm.nih.gov
In this study, we performed a comprehensively analysis of gene expression and DNA
methylation data to establish diagnostic, prognostic, and recurrence models for …

Hepatocellualar carcinoma serum markers

G Bertino, A Ardiri, M Malaguarnera… - Seminars in …, 2012 - Elsevier
Hepatocellular carcinoma (HCC) is one of the most common malignant tumors in some
areas of the world. In most cases, HCC is diagnosed at a late stage. Therefore, the …

Glycosylation and liver cancer

A Mehta, H Herrera, T Block - Advances in cancer research, 2015 - Elsevier
Liver cancer is the fifth most common cancer, but the second leading cause of cancer death,
in the world, with more than 700,000 fatalities annually. The major etiology of liver cancer is …

[HTML][HTML] Role of osteopontin in liver diseases

Y Wen, S Jeong, Q Xia, X Kong - International journal of biological …, 2016 - ncbi.nlm.nih.gov
Osteopontin (OPN), a multifunctional protein, is involved in numerous pathological
conditions including inflammation, immunity, angiogenesis, fibrogenesis and carcinogenesis …