Successful prediction of human fetal exposure to P-glycoprotein substrate drugs using the proteomics-informed relative expression factor approach and PBPK …
Many women take drugs during their pregnancy to treat a variety of clinical conditions. To
optimize drug efficacy and reduce fetal toxicity, it is important to determine or predict fetal …
optimize drug efficacy and reduce fetal toxicity, it is important to determine or predict fetal …
[图书][B] Predicting Human Fetal Drug Exposure to Placental P-glycoprotein Substrates by PBPK Modeling and Simulation
O Anoshchenko - 2021 - search.proquest.com
More than 80% of pregnant women take at least one drug during pregnancy and about 50%
during the first trimester when the fetus is the most vulnerable to drug toxicity (Scaffidi, Mol, & …
during the first trimester when the fetus is the most vulnerable to drug toxicity (Scaffidi, Mol, & …