[HTML][HTML] Nanostructured lipid carriers (NLCs) as drug delivery platform: Advances in formulation and delivery strategies

M Elmowafy, MM Al-Sanea - Saudi Pharmaceutical Journal, 2021 - Elsevier
NLCs have provoked the incessant impulsion for the development of safe and valuable drug
delivery systems owing to their exceptional physicochemical and then biocompatible …

Optimization of nanostructured lipid carriers: Understanding the types, designs, and parameters in the process of formulations

B Subramaniam, ZH Siddik, NH Nagoor - Journal of nanoparticle research, 2020 - Springer
Lipid-based nanoparticles for drug delivery have been employed in the development of
nanomedicine for various applications. One such versatile nanoparticle type is …

Nose-to-brain delivery of amisulpride-loaded lipid-based poloxamer-gellan gum nanoemulgel: In vitro and in vivo pharmacological studies

D Gadhave, S Tupe, A Tagalpallewar, B Gorain… - International Journal of …, 2021 - Elsevier
Unfavorable side effects of available antipsychotics limit the use of conventional delivery
systems, where limited exposure of the drugs to the systemic circulation could reduce the …

Biopharmaceutical and pharmacokinetic aspects of nanocarrier-mediated oral delivery of poorly soluble drugs

D Babadi, S Dadashzadeh, M Osouli… - Journal of Drug Delivery …, 2021 - Elsevier
Many new chemical entities have limited water solubility and therefore show low and/or
variable oral bioavailability. Among the various strategies to overcome this challenge …

Application of intranasal administration in the delivery of antidepressant active ingredients

Z Jin, Y Han, D Zhang, Z Li, Y Jing, B Hu, S Sun - Pharmaceutics, 2022 - mdpi.com
As a mental disease in modern society, depression shows an increasing occurrence, with
low cure rate and high recurrence rate. It has become the most disabling disease in the …

Nanostructured lipid carriers for improved delivery of therapeutics via the oral route

AK Mahor, PP Singh, R Gupta… - Journal of …, 2023 - Wiley Online Library
Drug delivery via the oral route has always been challenging for poorly soluble drugs. Acid‐
induced hydrolysis, enzymatic degradation, and poor mucosal absorbency remain the …

Preparation of ergosterol-loaded nanostructured lipid carriers for enhancing oral bioavailability and antidiabetic nephropathy effects

Z Dong, S Iqbal, Z Zhao - AAPS PharmSciTech, 2020 - Springer
In our previously studies, we confirmed that ergosterol could ameliorate diabetic
nephropathy by suppressing the proliferation of mesangial cells and the accumulation of …

Development of andrographolide-loaded solid lipid nanoparticles for lymphatic targeting: Formulation, optimization, characterization, in vitro, and in vivo evaluation

S Shrivastava, CD Kaur - Drug Delivery and Translational Research, 2023 - Springer
Andrographolide, the primary bioactive constituent of Andrographis paniculata, is a
promising natural substance with numerous pharmacotherapy uses. Low water solubility …

Nano spray-dried drugs for oral administration: A review

AA Öztürk, C Arpagaus - ASSAY and Drug Development …, 2021 - liebertpub.com
Spray drying is an important technology that is fast, simple, reproducible, and scalable. It has
a wide application range, that is, in food, chemicals, and encapsulation of pharmaceuticals …

Atorvastatin loaded lecithin-coated zein nanoparticles based thermogel for the intra-articular management of osteoarthritis: in-silico, in-vitro, and in-vivo studies

HA Elgendy, AMA Makky, YE Elakkad… - Journal of …, 2024 - Springer
Purpose Up-to-date literature offers limited data about utilizing atorvastatin calcium (ATV) as
a promising chondroprotective agent in osteoarthritis (OA). So, this study aims to develop a …