Applications of bioluminescence in biotechnology and beyond

AJ Syed, JC Anderson - Chemical Society Reviews, 2021 - pubs.rsc.org
Bioluminescence is the fascinating natural phenomenon by which living creatures produce
light. Bioluminescence occurs when the oxidation of a small-molecule luciferin is catalysed …

Brightening up Biology: Advances in Luciferase Systems for in Vivo Imaging

S Liu, Y Su, MZ Lin, JA Ronald - ACS chemical biology, 2021 - ACS Publications
Bioluminescence imaging (BLI) using luciferase reporters is an indispensable method for
the noninvasive visualization of cell populations and biochemical events in living animals …

Development and applications of bioluminescent and chemiluminescent reporters and biosensors

HW Yeh, HW Ai - Annual Review of Analytical Chemistry, 2019 - annualreviews.org
Although fluorescent reporters and biosensors have become indispensable tools in
biological and biomedical fields, fluorescence measurements require external excitation …

[HTML][HTML] Chemiluminescence and bioluminescence imaging for biosensing and therapy: in vitro and in vivo perspectives

Y Yan, P Shi, W Song, S Bi - Theranostics, 2019 - ncbi.nlm.nih.gov
Chemiluminescence (CL) and bioluminescence (BL) imaging technologies, which require
no external light source so as to avoid the photobleaching, background interference and …

A luciferase prosubstrate and a red bioluminescent calcium indicator for imaging neuronal activity in mice

X Tian, Y Zhang, X Li, Y Xiong, T Wu, HW Ai - Nature Communications, 2022 - nature.com
Although fluorescent indicators have been broadly utilized for monitoring bioactivities,
fluorescence imaging, when applied to mammals, is limited to superficial targets or requires …

Firefly-mimicking intensive and long-lasting chemiluminescence hydrogels

Y Liu, W Shen, Q Li, J Shu, L Gao, M Ma… - Nature …, 2017 - nature.com
Most known chemiluminescence (CL) reactions exhibit flash-type light emission. Great
efforts have been devoted to the development of CL systems that emit light with high …

Orthogonal luciferase–luciferin pairs for bioluminescence imaging

KA Jones, WB Porterfield, CM Rathbun… - Journal of the …, 2017 - ACS Publications
Bioluminescence imaging with luciferase–luciferin pairs is widely used in biomedical
research. Several luciferases have been identified in nature, and many have been adapted …

Recent achievements of bioluminescence imaging based on firefly luciferin-luciferase system

S Li, Z Ruan, H Zhang, H Xu - European Journal of Medicinal Chemistry, 2021 - Elsevier
Bioluminescence imaging (BLI) is a newly developed noninvasive visual approach which
facilitates the understanding of a plethora of biological processes in vitro and in vivo due to …

Long-Lasting and Intense Chemiluminescence of Luminol Triggered by Oxidized gC3N4 Nanosheets

X Sun, J Lei, Y Jin, B Li - Analytical Chemistry, 2020 - ACS Publications
Most of the known chemiluminescence (CL) systems are flash-type, whereas a CL system
with long-lasting and strong emission is very favorable for accurate CL quantitative analysis …

Bioluminescent turn-on probe for sensing hypochlorite in vitro and in tumors

P Chen, Z Zheng, Y Zhu, Y Dong, F Wang… - Analytical …, 2017 - ACS Publications
Hypochlorite (ClO–) is one of the most important reactive oxygen species but using a BL
probe for its selective detection (or imaging) still remains challenging. Herein, we report a …