[HTML][HTML] Estimating explainable Alzheimer's disease likelihood map via clinically-guided prototype learning

AW Mulyadi, W Jung, K Oh, JS Yoon, KH Lee, HI Suk - NeuroImage, 2023 - Elsevier
Identifying Alzheimer's disease (AD) involves a deliberate diagnostic process owing to its
innate traits of irreversibility with subtle and gradual progression. These characteristics make …

[HTML][HTML] Identifying underlying patterns in Alzheimer's disease trajectory: a deep learning approach and Mendelian randomization analysis

F Yi, Y Zhang, J Yuan, Z Liu, F Zhai, A Hao, F Wu… - …, 2023 - thelancet.com
Background Alzheimer's disease (AD) is a heterogeneously progressive neurodegeneration
disorder with varied rates of deterioration, either between subjects or within different stages …

[HTML][HTML] Explainability of random survival forests in predicting conversion risk from mild cognitive impairment to Alzheimer's disease

A Sarica, F Aracri, MG Bianco, F Arcuri, A Quattrone… - Brain Informatics, 2023 - Springer
Abstract Random Survival Forests (RSF) has recently showed better performance than
statistical survival methods as Cox proportional hazard (CPH) in predicting conversion risk …

Conversion from mild cognitive impairment to Alzheimer's disease: a comparison of tree-based machine learning algorithms for survival analysis

A Sarica, F Aracri, MG Bianco, MG Vaccaro… - … conference on brain …, 2023 - Springer
Prediction of conversion from Mild Cognitive Impairment (MCI) to Alzheimer's disease (AD)
is usually performed with Machine Learning (ML) supervised approaches. However, typical …

[HTML][HTML] Constructing personalized characterizations of structural brain aberrations in patients with dementia using explainable artificial intelligence

EH Leonardsen, K Persson, E Grødem, N Dinsdale… - npj Digital …, 2024 - nature.com
Deep learning approaches for clinical predictions based on magnetic resonance imaging
data have shown great promise as a translational technology for diagnosis and prognosis in …

[HTML][HTML] Essential New Complex-Based Themes for Patient-Centered Diagnosis and Treatment of Dementia and Predementia in Older People: Multimorbidity and …

E Wertman - Journal of Clinical Medicine, 2024 - mdpi.com
Dementia is a highly prevalent condition with devastating clinical and socioeconomic
sequela. It is expected to triple in prevalence by 2050. No treatment is currently known to be …

[HTML][HTML] Differential diagnosis of frontotemporal dementia subtypes with explainable deep learning on structural MRI

D Ma, J Stocks, H Rosen, K Kantarci… - Frontiers in …, 2024 - frontiersin.org
Background Frontotemporal dementia (FTD) represents a collection of neurobehavioral and
neurocognitive syndromes that are associated with a significant degree of clinical …

Predicting Alzheimer's Disease Diagnosis Risk Over Time with Survival Machine Learning on the ADNI Cohort

H Musto, D Stamate, I Pu, D Stahl - International Conference on …, 2023 - Springer
The rise of Alzheimer's Disease worldwide has prompted a search for efficient tools which
can be used to predict deterioration in cognitive decline leading to dementia. In this paper …

Predicting progression to clinical Alzheimer's disease dementia using the random survival forest

S Song, B Asken, MJ Armstrong… - Journal of Alzheimer's …, 2023 - content.iospress.com
Predicting Progression to Clinical Alzheimer’s Disease Dementia Using the Random Survival
Forest - IOS Press You are viewing a javascript disabled version of the site. Please enable …

[HTML][HTML] Early detection of dementia with default-mode network effective connectivity

S Ereira, S Waters, A Razi, CR Marshall - Nature Mental Health, 2024 - nature.com
Altered functional connectivity precedes structural brain changes and symptoms in
dementia. Alzheimer's disease is the largest contributor to dementia at the population level …