Plant-derived natural products have long been considered a valuable source of lead
compounds for drug development. Natural extracts are usually composed of hundreds to …

The screening and testing of extracts against a variety of pharmacological targets in order to
benefit from the immense natural chemical diversity is a concern in many laboratories …

Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

Recently, the high analytical power provided by the new HRMS instruments (working in the
MS or MS/MS mode, stand alone or hyphenated with separation techniques) is making more …

Covering: 2016 up to 2021 Mass spectrometry (MS) is an essential technology in natural
products research with MS fragmentation (MS/MS) approaches becoming a key tool. Recent …

Higher plant constituents have afforded clinically available anticancer drugs. These include
both chemically unmodified small molecules and their synthetic derivatives currently used or …

In this paper, quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical
scavenging profiling combined with HPLC-HRMS-SPE-NMR were used for studying the …

Discovery of sustainable and benign-by-design drugs to combat emerging health
pandemics calls for new analytical technologies to explore the chemical and …

Protein hydrolysates from food-processing byproducts are valuable sources of peptides,
often diverse in structure and bioactivity. This attribute makes them particularly interesting as …

Serrulatanes constitute a class of unique diterpenoids derived from all-Z nerylneryl
diphosphate rather than the conventional all-E diterpenoid precursor geranylgeranyl …