Recent advances in the system biology-based target identification and drug discovery

BS Yadav, V Tripathi - Current Topics in Medicinal Chemistry, 2018 - ingentaconnect.com
The enormous quantity of publicly available active chemical ligand and biological receptor
data knowledge allows scientists to retreat several open questions by the analysis and …

Matrix metalloproteinases (MMPs) in cancer immunotherapy

PK Yadav, M Ghosh, M Kataria - Handbook of Oxidative Stress in Cancer …, 2022 - Springer
Matrix metalloproteinases (MMPs) are the zinc-dependent endopeptidases that mediate the
degradation of the extracellular matrix (ECM) constituents and basement membrane to …

[HTML][HTML] Expression of MMP-2 and TIMP‑3 with incidence and prognosis of giant-cell tumor of the bone

Z Liu, Y Ren, F Zhu - Oncology Letters, 2018 - spandidos-publications.com
The expression of matrix metalloproteinase-2 (MMP-2) and tissue inhibitor of matrix
metalloproteinase-3 (TIMP-3) in giant-cell tumor of bone (GCT), and the correlation of their …

Protein modeling, molecular network and molecular dynamics study of newly sequenced interleukin‐18 (IL‐18) gene in Mus musculus

BS Yadav, N Chaturvedi, PK Yadav… - Journal of cellular …, 2019 - Wiley Online Library
Abstract Interleukin‐18 (IL‐18) belongs to the superfamily of IL‐1 protein and exerts a
pleiotropic pro‐inflammatory effect on the body. Generally, this protein is significantly …

Synthesis and characterization of oxygen depleted tert-amine calix[4]arene ligands and study the effect on sigma non-opioid intracellular protein receptor

N Chaturvedi, A Mishra, V Rawat - Structural Chemistry, 2019 - Springer
This study focuses on the biological prospects of oxygen-depleted calix [4] arene ligands on
a protein target. Because of their extensive medical relevance, the oxygen-depleted bis …