A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

Changes in the composition of gut-associated microbial communities are associated with
many human illnesses, but the factors driving dysbiosis remain incompletely understood …

Efforts to model the human gut microbiome in mice have led to important insights into the
mechanisms of host-microbe interactions. However, the model communities studied to date …

The human gut microbiome plays an important role in resisting colonization of the host by
pathogens, but we lack the ability to predict which communities will be protective. We …

A Western-style, high-fat diet promotes cardiovascular disease, in part because it is rich in
choline, which is converted to trimethylamine (TMA) by the gut microbiota. However, whether …

Reproducible science requires transparent reporting. The ARRIVE guidelines (Animal
Research: Reporting of In Vivo Experiments) were originally developed in 2010 to improve …

Improving the reproducibility of biomedical research is a major challenge. Transparent and
accurate reporting is vital to this process; it allows readers to assess the reliability of the …

Clostridium butyricum is a butyrate-producing human gut symbiont that has been safely
used as a probiotic for decades. C. butyricum strains have been investigated for potential …

INTRODUCTION One fundamental property of the immune system is its ability to develop
memory of previous encounters, resulting in enhanced responsiveness to subsequent …

Environmental light cycles entrain circadian feeding behaviors in animals that produce
rhythms in exposure to foodborne bacteria. Here, we show that the intestinal microbiota …