Spinal cord injury: molecular mechanisms and therapeutic interventions

X Hu, W Xu, Y Ren, Z Wang, X He, R Huang… - Signal transduction and …, 2023 - nature.com
Spinal cord injury (SCI) remains a severe condition with an extremely high disability rate.
The challenges of SCI repair include its complex pathological mechanisms and the …

Effects of durotomy versus myelotomy in the repair of spinal cord injury

D Telemacque, FZ Zhu, ZW Ren, KF Chen… - Neural regeneration …, 2020 - journals.lww.com
Current management for spinal cord injury aims to reduce secondary damage and recover
sensation and movement. Acute spinal cord injury is often accompanied by spinal cord …

Effect of durotomy versus myelotomy on tissue sparing and functional outcome after spinal cord injury

ZZ Khaing, LN Cates, DM Dewees, JE Hyde… - Journal of …, 2021 - liebertpub.com
Various surgical strategies have been developed to alleviate elevated intraspinal pressure
(ISP) following acute traumatic spinal cord injury (tSCI). Surgical decompression of either the …

Internal decompression of the acutely contused spinal cord: Differential effects of irrigation only versus biodegradable scaffold implantation

JD Guest, SW Moore, AA Aimetti, AB Kutikov… - Biomaterials, 2018 - Elsevier
Severe spinal cord injury leads to hemorrhage, edema and elevated tissue pressures that
propagate ischemia. Liquefactive necrosis of damaged tissue eventually results in chronic …

A review of strategies associated with surgical decompression in traumatic spinal cord injury

Y Zhu, F Lu, G Zhang, Z Liu - Journal of Neurological Surgery …, 2023 - thieme-connect.com
Traumatic spinal cord injury (TSCI) is frequent. Timely diagnosis and treatment have
reduced the mortality, but the long-term recovery of neurologic functions remains ominous …

Recovery after spinal cord injury by modulation of the proteoglycan receptor PTPσ

S Rink, D Arnold, A Wöhler, H Bendella, C Meyer… - Experimental …, 2018 - Elsevier
SCI is followed by dramatic upregulation of chondroitin sulfate proteoglycans (CSPGs)
which limit axonal regeneration, oligodendrocyte replacement and remyelination. The recent …

[Retracted] Medical Communication Services after Traumatic Spinal Cord Injury

J Alshorman, Y Wang, F Zhu, L Zeng… - Journal of …, 2021 - Wiley Online Library
It is difficult to assess and monitor the spinal cord injury (SCI) because of its pathophysiology
after injury, with different degrees of prognosis and various treatment methods, including …

Duraplasty promotes functional recovery by alleviating intraspinal pressure and edema following severe spinal cord compression injury in rabbits: experimental …

C Yang, T He, J Ma, Q Wang, S Wang, G Wang… - The Spine Journal, 2024 - Elsevier
BACKGROUND After acute traumatic spinal cord injury (tSCI), various surgical strategies
have been developed to alleviate elevated intraspinal pressure (ISP) and secondary injury …

神经电生理监测硬脊膜切开减压治疗急性脊髓损伤过程中脊髓的功能变化

杨九杰, 李治, 王树杰, 田野, 赵伟 - 中国组织工程研究, 2023 - cjter.com
神经电生理监测硬脊膜切开减压治疗急性脊髓损伤过程中脊髓的功能变化 Page 1 1232|中国组织
工程研究|第27卷|第8期|2023年3月 中国组织工程研究 Chinese Journal of Tissue Engineering …

Motor, sensitive, and vegetative recovery in rats with compressive spinal-cord injury after combined treatment with erythropoietin and whole-body vibration

S Rink, ME Manthou, J Arnold, M Grigo… - Restorative …, 2021 - content.iospress.com
Background: Physical therapy with whole body vibration (WBV) following compressive
spinal cord injury (SCI) in rats restores density of perisomatic synapses, improves body …