Na+/H+ exchangers play pivotal roles in the control of cell and tissue pH by mediating the
electroneutral exchange of Na+ and H+ across cellular membranes. They belong to an …

The NHE family of ion exchangers includes six isoforms (NHE1–NHE6) that function in an
electroneutral exchange of intracellular H+ for extracellular Na+. This review focuses on the …

This work presents a review of pH measurement methods and applications in cancers.
Magnetic resonance spectroscopic imaging and magnetic resonance imaging …

I. Introduction sources on the planet are Chilean nitrate deposits, California oil well brines,
and sea water. The transport of iodide (I-) is a highly specialized I-transport into the thyroid is …

In recent years, it has become evident that the volume of a given cell is an important factor
not only in defining its intracellular osmolality and its shape, but also in defining other …

This review describes recent progress concerning the molecular aspects of the Na+/H+
exchanger. The Na+/H+ exchanger is an important regulator for intracellular pH, cell volume …

Looked at from the genetic point-of-view cancer represents a daunting and, frankly,
confusing multiplicity of diseases (at least 100) that require an equally large variety of …

Protein kinase C represents a structurally homologous group of proteins similar in size,
structure and mechanism of activation. They can modulate the biological function of proteins …

The mammalian NHE (Na+/H+ exchanger) is a ubiquitously expressed integral membrane
protein that regulates intracellular pH by removing a proton in exchange for an extracellular …

Maintaining intracellular pH values close to neutrality is a crucial task for a wide variety of
cells. Hence, various mechanisms for pH regulation have been selected early in evolution …