At the plasma membrane, gangliosides, a group of glycosphingolipids, are expressed along
with glycosphingolipids, phospholipids, and cholesterol in so-called lipid rafts that interact …

Successful therapy and diagnosis of glioma is one of the biggest challenges in the
biomedical fields. The incidence is growing gradually around the world. Annually, there are …

The aim of this study was to investigate the expression and function of the transient receptor
potential vanilloid 2 (TRPV2) in human glioma cells. By Real-Time–PCR and western blot …

Gastroenteropancreatic neuroendocrine neoplasms are heterogeneous in their clinical
behavior and require therapies specially tailored according to staging, grading, origin and …

Our results demonstrate the first findings of expression and function of the purinergic P2X7
receptor (P2X7R) in rat C6 glioma cells. P2X7R mRNA and protein were present in …

High-content analysis (HCA) combines automated microscopy and automated image
analysis to quantify complex cellular anatomy and biochemistry objectively, accurately and …

Imatinib was the first targeted tyrosine kinase inhibitor to be approved for clinical use and
remains first-line therapy for Philadelphia chromosome (Ph+)-positive chronic myelogenous …

Glioblastoma (GBM) is the most common malignant primary brain tumor. It still carries a grim
prognosis and new therapies are needed. This review summarizes the current status of …

Capsaicin (8-methyl-N-vanillyl-6-nonenamide), the major pungent ingredient of red pepper,
has been reported to possess anti-carcinogenic and anti-mutagenic activities. In this study …

Loss-of-function DJ-1 mutations have been linked to autosomal recessive early-onset
Parikinsonism. However, the putative function of DJ-1 is not completely understood …