Immunomodulatory biomaterials for tissue repair

R Whitaker, B Hernaez-Estrada… - Chemical …, 2021 - ACS Publications
All implanted biomaterials are targets of the host's immune system. While the host
inflammatory response was once considered a detrimental force to be blunted or avoided, in …

Scaffolding biomaterials for 3D cultivated meat: prospects and challenges

C Bomkamp, SC Skaalure, GF Fernando… - Advanced …, 2022 - Wiley Online Library
Cultivating meat from stem cells rather than by raising animals is a promising solution to
concerns about the negative externalities of meat production. For cultivated meat to fully …

Shattering barriers toward clinically meaningful MSC therapies

O Levy, R Kuai, EMJ Siren, D Bhere, Y Milton… - Science …, 2020 - science.org
More than 1050 clinical trials are registered at FDA. gov that explore multipotent
mesenchymal stromal cells (MSCs) for nearly every clinical application imaginable …

[HTML][HTML] Therapeutic strategies of three-dimensional stem cell spheroids and organoids for tissue repair and regeneration

W Kim, Y Gwon, S Park, H Kim, J Kim - Bioactive Materials, 2023 - Elsevier
Abstract Three-dimensional (3D) stem cell culture systems have attracted considerable
attention as a way to better mimic the complex interactions between individual cells and the …

Macrophage phenotypes in tissue repair and the foreign body response: Implications for biomaterial-based regenerative medicine strategies

KE Martin, AJ García - Acta biomaterialia, 2021 - Elsevier
Macrophages are a highly heterogeneous and plastic population of cells that are crucial for
tissue repair and regeneration. This has made macrophages a particularly attractive target …

Recent advances in regenerative biomaterials

D Cao, J Ding - Regenerative Biomaterials, 2022 - academic.oup.com
Nowadays, biomaterials have evolved from the inert supports or functional substitutes to the
bioactive materials able to trigger or promote the regenerative potential of tissues. The …

Hydrogel as a biomaterial for bone tissue engineering: A review

S Yue, H He, B Li, T Hou - Nanomaterials, 2020 - mdpi.com
Severe bone damage from diseases, including extensive trauma, fractures, and bone
tumors, cannot self-heal, while traditional surgical treatment may bring side effects such as …

Effects of mesenchymal stem cell‐derived paracrine signals and their delivery strategies

C Chang, J Yan, Z Yao, C Zhang, X Li… - Advanced healthcare …, 2021 - Wiley Online Library
Mesenchymal stem cells (MSCs) have been widely studied as a versatile cell source for
tissue regeneration and remodeling due to their potent bioactivity, which includes …

Drug delivery systems based on polyethylene glycol hydrogels for enhanced bone regeneration

S Sun, Y Cui, B Yuan, M Dou, G Wang, H Xu… - … in bioengineering and …, 2023 - frontiersin.org
Drug delivery systems composed of osteogenic substances and biological materials are of
great significance in enhancing bone regeneration, and appropriate biological carriers are …

Combinatorial treatment rescues tumour-microenvironment-mediated attenuation of MALT1 inhibitors in B-cell lymphomas

SB Shah, CR Carlson, K Lai, Z Zhong, G Marsico… - Nature materials, 2023 - nature.com
Activated B-cell-like diffuse large B-cell lymphomas (ABC-DLBCLs) are characterized by
constitutive activation of nuclear factor κB driven by the B-cell receptor (BCR) and Toll-like …