RNA helicases are highly conserved proteins that use nucleoside triphosphates to bind or
remodel RNA, RNA–protein complexes or both. RNA helicases are classified into the DEAD …

Nonsense-mediated mRNA decay (NMD) is one of the best characterized and most
evolutionarily conserved cellular quality control mechanisms. Although NMD was first found …

Abstract mRNA surveillance pathways are essential for accurate gene expression and to
maintain translation homeostasis, ensuring the production of fully functional proteins. Future …

Nonsense-mediated mRNA decay (NMD) is arguably the best-studied eukaryotic
messenger RNA (mRNA) surveillance pathway, yet fundamental questions concerning the …

Nonsense‐mediated mRNA decay (NMD) was originally coined to define a quality control
mechanism that targets mRNAs with truncated open reading frames due to the presence of a …

The inclusion of familial myeloid malignancies as a separate disease entity in the revised
WHO classification has renewed efforts to improve the recognition and management of this …

Steady-state RNA levels are controlled by the balance between RNA synthesis and RNA
turnover. A selective RNA turnover mechanism that has received recent attention in neurons …

Nonsense-mediated mRNA decay (NMD) is a conserved translation-coupled quality control
mechanism in all eukaryotes that regulates the expression of a significant fraction of both the …

Nonsense-mediated decay (NMD) was first described as a quality-control mechanism that
targets and rapidly degrades aberrant mRNAs carrying premature termination codons …

Nonsense-mediated mRNA decay (NMD), which is arguably the best-characterized
translation-dependent regulatory pathway in mammals, selectively degrades mRNAs as a …