An interplay between non-coding RNAs and gut microbiota in human health

F Fardi, LB Khasraghi, N Shahbakhti… - Diabetes Research and …, 2023 - Elsevier
Humans have a complicated symbiotic relationship with their gut microbiome, which is
postulated to impact host health and disease broadly. Epigenetic alterations allow host cells …

Gut microbiome in non-alcoholic fatty liver disease: from mechanisms to therapeutic role

H Gupta, BH Min, R Ganesan, YA Gebru, SP Sharma… - Biomedicines, 2022 - mdpi.com
Non-alcoholic fatty liver disease (NAFLD) is considered to be a significant health threat
globally, and has attracted growing concern in the research field of liver diseases. NAFLD …

Rosavin ameliorates hepatic inflammation and fibrosis in the NASH rat model via targeting hepatic cell death

R Albadawy, AH Hasanin, SHA Agwa… - International journal of …, 2022 - mdpi.com
Background: Non-alcoholic fatty liver disease (NAFLD) represents the most common form of
chronic liver disease that urgently needs effective therapy. Rosavin, a major constituent of …

Gut microbiota–lncRNA/circRNA crosstalk: implications for different diseases

L Zhang, X Li, H Gao, W Chang, P Li - Critical Reviews in …, 2024 - Taylor & Francis
The gut microbiota features an abundance of diverse microorganisms and represents an
important component of human physiology and metabolic homeostasis, indicating their roles …

Lactobacillus rhamnosus GG ameliorates radiation-induced lung fibrosis via lncRNASNHG17/PTBP1/NICD axis modulation

Z Ju, H Pan, C Qu, L Xiao, M Zhou, Y Wang, J Luo… - Biology Direct, 2023 - Springer
Radiation-induced pulmonary fibrosis (RIPF) is a major side effect experienced for patients
with thoracic cancers after radiotherapy. RIPF is poor prognosis and limited therapeutic …

Sodium acetate inhibit TGF-β1-induced activation of hepatic stellate cells by restoring AMPK or c-Jun signaling

W Li, M Deng, J Gong, X Zhang, S Ge, L Zhao - Frontiers in Nutrition, 2021 - frontiersin.org
Short-chain fatty acids (SCFAs) are crucial gut microbial metabolites that play a major role in
the occurrence and development of hepatic fibrosis (HF). However, the effect of SCFAs on …

A mini-review on prebiotic inulin to prevent and treat non-alcoholic fatty liver disease

N Kei, S Lauw, VWS Wong, PCK Cheung - Food Bioscience, 2024 - Elsevier
Given the increasing worldwide prevalence of non-alcoholic fatty liver disease (NAFLD) and
a lack of approved medication, the development of effective nutritional supplements for …

Evaluation of the role of kefir in management of non-alcoholic steatohepatitis rat model via modulation of NASH linked mRNA-miRNA panel

N Salah, S Eissa, A Mansour, NMA El Magd… - Scientific Reports, 2023 - nature.com
Non-alcoholic steatohepatitis (NASH) is the clinically aggressive variant of non-alcoholic
fatty liver disease. Hippo pathway dysregulation can contribute to NASH development and …

Machine learning based identification potential feature genes for prediction of drug efficacy in nonalcoholic steatohepatitis animal model

M Matboli, I Abdelbaky, A Khaled, R Khaled… - Lipids in Health and …, 2024 - Springer
Abstract Background Nonalcoholic Steatohepatitis (NASH) results from complex liver
conditions involving metabolic, inflammatory, and fibrogenic processes. Despite its burden …

Updated Insights into Probiotics and Hepatobiliary Diseases

X Xu, C Zhang, G Tang, N Wang, Y Feng - Biomedicines, 2024 - mdpi.com
Hepatobiliary diseases have a high prevalence worldwide, with a wide range of diseases
involved in the liver and biliary system. Modifications in gut microbiota have been proven to …