The Western-style diet is characterized by its highly processed and refined foods and high
contents of sugars, salt, and fat and protein from red meat. It has been recognized as the …

Diabetic nephropathy is an increasingly important cause of morbidity and mortality
worldwide. A large body of evidence suggests that dyslipidemia has an important role in the …

Streptozotocin (STZ) is an antibiotic that produces pancreatic islet β‐cell destruction and is
widely used experimentally to produce a model of type 1 diabetes mellitus (T1DM). Detailed …

Streptozotocin (STZ) is an antibiotic that causes pancreatic islet β‐cell destruction and is
widely used experimentally to produce a model of type 1 diabetes mellitus (T1DM). Detailed …

Diabetic nephropathy (DN) is one of the main complications of diabetes. However, effective
therapy to block or slow down the progression of DN is still lacking. San-Huang-Yi-Shen …

Cytochrome P450 eicosanoids in hypertension and renal diseas... : Current Opinion in
Nephrology and Hypertension Cytochrome P450 eicosanoids in hypertension and renal disease …

Thirty-five years ago, a third pathway for the metabolism of arachidonic acid by cytochrome
P450 enzymes emerged. Subsequent work revealed that 20-hydroxyeicosatetraenoic and …

In humans, four members of the CYP2C subfamily (CYP2C8, CYP2C9, CYP2C18, and
CYP2C19) metabolize more than 20% of all therapeutic drugs as well as a number of …

Arachidonic acid (AA) is metabolized by cyclooxygenase (COX), lipoxygenase (LOX), and
cytochrome P450 (CYP) enzymes into eicosanoids, which are involved in diverse diseases …

Arachidonic acid (AA) is a main component of cell membrane lipids. AA is mainly
metabolized by three enzymes: cyclooxygenase (COX), lipoxygenase (LOX) and …