Head and neck cancer (HNC) encompasses a heterogeneous group of upper aerodigestive
tract malignancies that together comprise the seventh most common cancer worldwide, 1 …

Survival from head and neck cancers (HNCs) of the lip, oral cavity, pharynx, and larynx has
increased by 10% over the past few decades. Little over half of patients who develop HNCs …

Context Human papillomavirus (HPV) is a major cause of oropharyngeal squamous cell
carcinomas, and HPV (and/or surrogate marker p16) status has emerged as a prognostic …

Cellular senescence is a state of stable cell-cycle arrest with secretory features in response
to cellular stress. Historically, it has been considered as an endogenous evolutionary …

Human Papillomavirus (HPV) related oropharyngeal squamous cell carcinomas (OPSCCs)
are reported to have improved prognosis and survival in comparison to other head and neck …

PURPOSE To provide evidence-based recommendations to practicing physicians and other
health care providers on the diagnosis and management of squamous cell carcinoma of …

Tumor human papillomavirus (HPV) status is a prognostic factor for oropharyngeal cancer,
but classification methods are not standardized. Here we validate the HPV classification …

Evidence for transcriptional activation of the viral oncoproteins E6 and E7 is regarded as the
gold standard for the presence of clinically relevant human papillomavirus (HPV), but …

Recent studies of oropharyngeal carcinoma have reported remarkable correlation between
integrated human papillomavirus (HPV) viral detection and p16 protein overexpression in …

Abstract Purpose: Human papillomavirus-16 (HPV16) is the causative agent in a biologically
distinct subset of oropharyngeal squamous cell carcinoma (OPSCC) with highly favorable …