Synthesis of 1-Methylcyclopropyl Aryl Ethers from Phenols Using an Alkenylation-Cyclopropanation Sequence
B Bueno, S Heurtaux, A Gagnon - The Journal of Organic …, 2023 - ACS Publications
1-Methylcyclopropyl aryl ethers (McPAEs) can be viewed as cyclized derivatives of their O-
tert-butyl counterparts. Although these compounds can find use in medicinal chemistry, they …
tert-butyl counterparts. Although these compounds can find use in medicinal chemistry, they …
Design, dynamic docking, synthesis, and in vitro validation of a novel DNA gyrase B inhibitor
Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin-intermediate-resistant
Staphylococcus aureus (VRSA) are among the WHO's high priority pathogens. Among these …
Staphylococcus aureus (VRSA) are among the WHO's high priority pathogens. Among these …
SNAr or Sulfonylation? Chemoselective Amination of Halo(het)arene Sulfonyl Halides for Synthetic Applications and Ultralarge Compound Library Design
V Naumchyk, VA Andriashvili… - The Journal of …, 2024 - ACS Publications
The chemoselectivity of halo (het) arene sulfonyl halide aminations is studied thoroughly
under parallel synthesis conditions, and the scope and limitations of the method are …
under parallel synthesis conditions, and the scope and limitations of the method are …
CycA-Dependent Glycine Assimilation Is Connected to Novobiocin Susceptibility in Escherichia coli
H Shi, L Zhang, J Gu, J Li, Z Liu… - Microbiology Spectrum, 2022 - Am Soc Microbiol
Escherichia coli serine hydroxymethyltransferase (GlyA) converts serine to glycine, and glyA
mutants are auxotrophic for glycine. CycA is a transporter that mediates glycine uptake …
mutants are auxotrophic for glycine. CycA is a transporter that mediates glycine uptake …
Analysis of the potential of active compounds in cloves (Syzygium aromaticum) as candidates for anti-typhoid drugs based on molecular docking
M Amin, C Zakinah, B Lukiati… - AIP Conference …, 2023 - pubs.aip.org
Typhoid fever is a disease caused by infection with the pathogenic bacteria Salmonella
typhi. Typhoid fever treatment usually uses antibiotics, but currently many typhoid fever …
typhi. Typhoid fever treatment usually uses antibiotics, but currently many typhoid fever …
Non-quinolone topoisomerase inhibitors
Fluoroquinolone antibiotics, such as ciprofloxacin, levofloxacin, and moxifloxacin, have
enjoyed enormous success over the past few decades. However, resistance to these …
enjoyed enormous success over the past few decades. However, resistance to these …
Synthesis, structure, photophysical, electrochemical properties and antibacterial activity of brominated BODIPYs as an inhibitor of DNA gyrase B of S. aureus
D Prasannan, C Sareena, C Arunkumar… - Journal of Porphyrins …, 2019 - World Scientific
BODIPYs with 3-thienyl and 4-acetamido phenyl groups substituted at the meso-position are
subjected to regioselective bromination using three equivalents of N-bromosuccinimide …
subjected to regioselective bromination using three equivalents of N-bromosuccinimide …
Design of a novel DNA Gyrase B inhibitor with a rhodanine scaffold: in silico and in vitro approaches
A Pudipeddi, S Vasudevan, K Shanmugam, A Stanley… - bioRxiv, 2021 - biorxiv.org
Methicillin-resistant Staphylococcus aureus (MRSA) and vancomycin intermediate-resistant
Staphylococcus aureus (VRSA) is one among the WHO high priority pathogens. Among …
Staphylococcus aureus (VRSA) is one among the WHO high priority pathogens. Among …
[引用][C] New therapy approach against E. coli ST131 infection: Nanoparticle based targeted antimicrobial agents
N Ataç - 2019 - Sağlık Bilimleri Enstitüsü