Allenes are a class of unique compounds with two π-orbitals perpendicular to each other.
The first synthesis can be traced back to 1887. 1 They also exist in many natural products …

Allenes have always fascinated chemists because of the intriguing features of the cumulated
diene function such as the higher reactivity compared to simple alkenes and the peculiar …

The development of effective small‐molecule probes and drugs entails at least three stages:
1) a discovery phase, often requiring the synthesis and screening of candidate compounds …

Allenes have allowed chemists to access a variety of structurally interesting and biologically
active products. The emergence of these unique compounds in organic synthesis is a direct …

Nitrene transfer reactions are powerful tools in synthetic organic chemistry. In recent years,
transition-metal catalyzed nitrene transfer reactions with carbamates as the nitrene …

Multidimensional reaction screening of ortho-alkynyl benzaldehydes with a variety of
catalysts and reaction partners was conducted in an effort to identify new chemical reactions …

The [2+ 2+ 1] cyclization of an alkyne, an alkene and carbon monoxide, ie, the Pauson–
Khand reaction, is one of the most powerful tools for constructing a five-membered ring. In …

The synthesis of cyclopentenones is most frequently achieved via an organometallic
approach. The widely studied route, the Pauson–Khand reaction (PKR), incorporates three …

Allenes are important 2π building blocks in organic synthesis and engage as 2-carbon
components in many metal-catalyzed reactions. Wender and co-workers discovered that …

Microwave irradiation of alkynyl allenes affords an intramolecular [2+ 2] cycloaddition
reaction. This cycloaddition provides an efficient route to bicyclomethylenecyclobutenes …