Inflammation plays an important role in the response to danger signals arising from damage
to our body and in restoring homeostasis. Dysregulated inflammatory responses occur in …

Venous leg ulcers (VLUs) are one of the most common ulcers of the lower extremity. VLU
affects many individuals worldwide, could pose a significant socioeconomic burden to the …

In today's modern era of medicine, macromolecular compounds such as proteins, peptides
and nucleic acids are dethroning small molecules as leading therapeutics. Given their …

The connexin family of channel-forming proteins is present in every tissue type in the human
anatomy. Connexins are best known for forming clustered intercellular channels, structurally …

Connexins are ubiquitous channel forming proteins that assemble as plasma membrane
hemichannels and as intercellular gap junction channels that directly connect cells. In the …

Gap junctions are essential to the function of multicellular animals, which require a high
degree of coordination between cells. In vertebrates, gap junctions comprise connexins and …

Cold plasma has been successfully applied in several fields of medicine that require, for
example, pathogen inactivation, implant functionalization or alteration of cellular activity …

Acute wound healing is an orderly process of four overlapping events: haemostasis,
inflammation, proliferation and remodelling. A drug delivery system with a temporal control …

Connexins are a family of transmembrane proteins that play a key role in cardiac physiology.
Gap junctional channels put into contact the cytoplasms of connected cardiomyocytes …

The accumulation of senescent cells is a key characteristic of aging, leading to the
progression of age-related diseases such as osteoarthritis (OA). Previous data from our …