The circadian clock is a timekeeping system for numerous biological rhythms that contribute
to the regulation of numerous homeostatic processes in humans. Disruption of circadian …

The circadian clock and cell metabolism are both dysregulated in cancer cells through
intrinsic cell-autonomous mechanisms and external influences from the tumor …

Mutation of the isocitrate dehydrogenase 1 (IDH1) gene leads to the production of
oncometabolite D-2-hydroxyglutarate (2-HG) from α-ketoglutarate and is associated with …

Increasing evidence suggests the oncogenic role of missense mutation (AKT1-E17K) of
AKT1 gene in meningiomas. Upon investigating the connection between the pro …

Glioblastoma is one of the most lethal cancers with current therapeutic options lacking major
successes. This underlines the necessity to understand glioblastoma biology on other levels …

In recent years, studies on circadian control in immunity have been actively conducted in
mammals, but little is known about circadian rhythms in the field of fish immunology. In this …

Epigenetic gene regulation in the heterogeneous brain remains challenging to decipher with
current strategies. Bulk tissue analysis from pooled subjects reflects the average of cell-type …

Circadian rhythm is a master process observed in nearly every type of cell throughout the
body, and it macroscopically regulates daily physiology. Recent clinical trials have revealed …

In an attempt to understand the role of dysregulated circadian rhythm in glioma, our recent
findings highlighted the existence of a feed-forward loop between tumour metabolite lactate …

Glioma is characterized as the most aggressive brain tumor that occurred in the central
nervous system. The circadian rhythm is an essential cyclic change system generated by the …