Ischemic cell death in brain neurons

P Lipton - Physiological reviews, 1999 - journals.physiology.org
This review is directed at understanding how neuronal death occurs in two distinct insults,
global ischemia and focal ischemia. These are the two principal rodent models for human …

Functional significance of cell volume regulatory mechanisms

F Lang, GL Busch, M Ritter, H Volkl… - Physiological …, 1998 - journals.physiology.org
Lang, Florian, Gillian L. Busch, Markus Ritter, Harald Völkl, Siegfried Waldegger, Erich
Gulbins, and Dieter Häussinger. Functional Significance of Cell Volume Regulatory …

[HTML][HTML] Water permeation drives tumor cell migration in confined microenvironments

KM Stroka, H Jiang, SH Chen, Z Tong, D Wirtz, SX Sun… - Cell, 2014 - cell.com
Cell migration is a critical process for diverse (patho) physiological phenomena. Intriguingly,
cell migration through physically confined spaces can persist even when typical hallmarks of …

Diversity of the mammalian sodium/proton exchanger SLC9 gene family

J Orlowski, S Grinstein - Pflügers Archiv, 2004 - Springer
Sodium/proton antiporters or exchangers (NHE) are integral membrane proteins present in
most, if not all, living organisms. In mammals, these transporters chiefly catalyze the …

The Changing Face of the Na+/H+ Exchanger, NHE1: Structure, Regulation, and Cellular Actions

LK Putney, SP Denker, DL Barber - Annual review of …, 2002 - annualreviews.org
The NHE family of ion exchangers includes six isoforms (NHE1–NHE6) that function in an
electroneutral exchange of intracellular H+ for extracellular Na+. This review focuses on the …

[HTML][HTML] Na+/H+ exchangers of mammalian cells

J Orlowski, S Grinstein - Journal of Biological Chemistry, 1997 - ASBMB
Ejection of intracellular H in exchange for external Na is the most effective means of
eliminating excess acid from actively metabolizing cells. Na/H exchange is also crucial for …

Molecular physiology of vertebrate Na+/H+ exchangers

S Wakabayashi, M Shigekawa… - Physiological …, 1997 - journals.physiology.org
This review describes recent progress concerning the molecular aspects of the Na+/H+
exchanger. The Na+/H+ exchanger is an important regulator for intracellular pH, cell volume …

The Myocardial Na+-H+ Exchange: Structure, Regulation, and Its Role in Heart Disease

M Karmazyn, XT Gan, RA Humphreys… - Circulation …, 1999 - Am Heart Assoc
The Na+-H+ exchange (NHE) is a major mechanism by which the heart adapts to
intracellular acidosis during ischemia and recovers from the acidosis after reperfusion …

Functional role of glucose metabolism, osmotic stress, and sodium-glucose cotransporter isoform-mediated transport on Na+/H+ exchanger isoform 3 activity in the …

TD Pessoa, LCG Campos… - Journal of the …, 2014 - journals.lww.com
Abstract Na+-glucose cotransporter 1 (SGLT1)-mediated glucose uptake leads to activation
of Na+-H+ exchanger 3 (NHE3) in the intestine by a process that is not dependent on …

cAMP-mediated inhibition of the epithelial brush border Na+/H+ exchanger, NHE3, requires an associated regulatory protein

CHC Yun, S Oh, M Zizak, D Steplock… - Proceedings of the …, 1997 - National Acad Sciences
NHE3 is the Na+/H+ exchanger located on the intestinal and renal brush border membrane,
where it functions in transepithelial Na+ absorption. The brush border Na+ absorptive …