Polyamine Metabolism for Drug Intervention in Trypanosomatids

Y Pérez-Pertejo, C García-Estrada… - Pathogens, 2024 - mdpi.com
Neglected tropical diseases transmitted by trypanosomatids include three major human
scourges that globally affect the world's poorest people: African trypanosomiasis or sleeping …

Investigational new drugs for the treatment of leishmaniasis

S Sundar, VK Singh, N Agrawal, OP Singh… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Over the past 20 years, significant progress has been made in anti-leishmanial
therapy. Three new drugs/formulations are available for the treatment of various forms of …

[HTML][HTML] Emerging Leishmania donovani Lineages Associated with Cutaneous Leishmaniasis, Himachal Pradesh, India, 2023

P Lypaczewski, Y Chauhan, K Paulini… - Emerging Infectious …, 2024 - pmc.ncbi.nlm.nih.gov
The clinical manifestation of leishmaniasis has historically been determined by the
Leishmania species involved. However, recent emergence of novel Leishmania lineages …

[HTML][HTML] Immunotherapeutic Strategies as Potential Treatment Options for Cutaneous Leishmaniasis

A Lafleur, S Daffis, C Mowbray, B Arana - Vaccines, 2024 - mdpi.com
Cutaneous leishmaniasis (CL), caused by protozoan parasites of the Leishmania genus, is
prevalent in tropical and subtropical regions, with important morbidity, particularly in low-to …

Atypical cutaneous leishmaniasis: a new challenge to VL elimination in South-East Asia

M Jain, DA Sangma, L Parida, R Negi… - Frontiers in Cellular …, 2024 - frontiersin.org
Visceral leishmaniasis (VL) caused by L. donovani in South-East Asian endemic countries
including India, Nepal and Bangladesh has been the primary focus of the ongoing VL …

Current and emerging therapies for the treatment of leishmaniasis

S Sundar, J Singh, VK Singh, N Agrawal… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Leishmaniasis, a neglected protozoan illness caused by kinetoplastid
pathogens encompasses three major clinical subtypes: visceral, cutaneous and …

Post-Kala-Azar Dermal Leishmaniasis

A Sharma, A Bishnoi, D Parsad - The American Journal of …, 2024 - pmc.ncbi.nlm.nih.gov
Post-Kala-Azar Dermal Leishmaniasis - PMC Skip to main content Here's how you know Official
websites use .gov A .gov website belongs to an official government organization in the United …

Patient insights research exploring disease awareness, patient life experience, and current management of visceral leishmaniasis in Bihar, India

S Sundar, F Alves, K Ritmeijer, M den Boer, C Forsyth… - medRxiv, 2024 - medrxiv.org
Background Visceral leishmaniasis (VL) is a vector-borne disease caused by Leishmania
parasites and transmitted by sand fly bites, targeted for elimination in India. VL primarily …