Oxidative stress in preterm newborns

C Lembo, G Buonocore, S Perrone - Antioxidants, 2021 - mdpi.com
Preterm babies are highly susceptible to oxidative stress (OS) due to an imbalance between
the oxidant and antioxidant systems. The generation of free radicals (FR) induces oxidative …

[HTML][HTML] Effects of 4-hydroxynonenal on vascular endothelial and smooth muscle cell redox signaling and function in health and disease

SJ Chapple, X Cheng, GE Mann - Redox biology, 2013 - Elsevier
hydroxynonenal (HNE) is a lipid hydroperoxide end product formed from the oxidation of n-6
polyunsaturated fatty acids. The relative abundance of HNE within the vasculature is …

Embryonal erythropoiesis and aging exploit ferroptosis

H Zheng, L Jiang, T Tsuduki, M Conrad, S Toyokuni - Redox biology, 2021 - Elsevier
Ferroptosis is a form of regulated cell necrosis, as a consequence of Fe (II)-dependent lipid
peroxidation. Although ferroptosis has been linked to cancer cell death, neurodegeneration …

[HTML][HTML] Prenatal neonicotinoid insecticides exposure, oxidative stress, and birth outcomes

C Pan, J Yu, Q Yao, N Lin, Z Lu, Y Zhang, S Zhao… - Environment …, 2022 - Elsevier
Background An increasing number of studies have reported neonicotinoid insecticides
(NEOs), the emerging alternatives to conventional insecticides, may increase oxidative …

The relevance of pathophysiological alterations in redox signaling of 4-hydroxynonenal for pharmacological therapies of major stress-associated diseases

M Jaganjac, L Milkovic, A Gegotek, M Cindric… - Free Radical Biology …, 2020 - Elsevier
Modern analytical methods combined with the modern concepts of redox signaling revealed
4-hydroxy-2-nonenal (4-HNE) as particular growth regulating factor involved in redox …

Antenatal antioxidant treatment with melatonin to decrease newborn neurodevelopmental deficits and brain injury caused by fetal growth restriction

SL Miller, T Yawno, NO Alers… - Journal of pineal …, 2014 - Wiley Online Library
Fetal intrauterine growth restriction (IUGR) is a serious pregnancy complication associated
with increased rates of perinatal morbidity and mortality, and ultimately with long‐term …

Preliminary findings on the association of the lipid peroxidation product 4-hydroxynonenal with the lethal outcome of aggressive COVID-19

N Žarković, B Orehovec, L Milković, B Baršić, F Tatzber… - Antioxidants, 2021 - mdpi.com
Major findings of the pilot study involving 21 critically ill patients during the week after
admission to the critical care unit specialized for COVID-19 are presented. Fourteen patients …

Advances in methods for the determination of biologically relevant lipid peroxidation products

CM Spickett, I Wiswedel, W Siems, K Zarkovic… - Free radical …, 2010 - Taylor & Francis
Lipid peroxidation is recognized to be an important contributor to many chronic diseases,
especially those of an inflammatory pathology. In addition to their value as markers of …

[HTML][HTML] Preterm birth and oxidative stress: Effects of acute physical exercise and hypoxia physiological responses

A Martin, C Faes, T Debevec, C Rytz, G Millet… - Redox biology, 2018 - Elsevier
Preterm birth is a global health issue that can induce lifelong medical sequela. Presently, at
least one in ten newborns are born prematurely. At birth, preterm newborns exhibit higher …

Assays for the measurement of lipid peroxidation

AC Gasparovic, M Jaganjac, B Mihaljevic… - … : Methods and Protocols, 2013 - Springer
Physical and emotional stress, metabolic alterations, carcinogenesis or inflammation are
conditions that can trigger oxidative stress, which is defined as a balance shift of redox …