Anorexia nervosa (AN) is a severe eating disorder affecting around 1 per 100 persons.
However, the knowledge about its underlying pathophysiology is limited. To address the …

Background The genesis of anorexia nervosa (AN), a severe eating disorder with a
pervasive effect on many brain functions such as attention, emotions, reward processing …

Agmatine, the decarboxylation product of arginine, was largely neglected as an important
player in mammalian metabolism until the mid-1990s, when it was re-discovered as an …

Chronic maternal ethanol exposure leads to poor intelligence, impaired cognition and array
of neurological symptoms in offsprings and commonly referred as fetal alcohol spectrum …

Agmatine, an endogenous polyamine in CNS, is derived from arginine by dearboxylation.
Like polyamines, agmatine has been studied for its neuroprotetive effects. At present, a large …

Anorexia nervosa (AN) is a severe psychiatric disorder without approved medication
intervention. Every class of psychoactive medication has been tried to improve treatment …

Major depressive disorder is the most common psychiatric disorder with lifetime prevalence
of up to 20% worldwide. It is responsible for more years lost to disability than any other …

Post-traumatic stress disorder (PTSD), is a severe anxiety disorder characterized by
associative fear conditioning. Single prolonged stress (SPS) is a widely accepted reliable …

Alzheimer's disease (AD) is a chronic and progressive neurodegenerative disorder
characterized by abnormal accumulation of extracellular β-amyloid (Aβ) plaques and …

Adaptive responses to stressful stimuli in the environment are believed to restore
homeostasis after stressful events. Stress activates the hypothalamic-pituitary-adrenocortical …