Associations between symptoms of premenstrual disorders and polygenic liability for major psychiatric disorders

P Jaholkowski, AA Shadrin, A Jangmo, E Frei… - JAMA …, 2023 - jamanetwork.com
Importance Premenstrual disorders are heritable, clinically heterogenous, with a range of
affective spectrum comorbidities. It is unclear whether genetic predispositions to affective …

The structure of psychiatric comorbidity without selection and assortative mating

Z Ayorech, FA Torvik, R Cheesman… - Translational …, 2024 - nature.com
The widespread comorbidity observed across psychiatric disorders may be the result of
processes such as assortative mating, gene-environment correlation, or selection into …

Disentangling direct and indirect genetic effects from partners and offspring on maternal depression using trio-GCTA

LD Bjørndal, EM Eilertsen, Z Ayorech… - Nature Mental …, 2024 - nature.com
Maternal depressive symptoms are highly prevalent and can negatively impact affected
individuals and family members. Understanding etiological influences on maternal …

Genetic Insights Into Perinatal Outcomes of Maternal Antihypertensive Therapy During Pregnancy

CJS Barry, VM Walker, C Burden, A Havdahl… - JAMA Network …, 2024 - jamanetwork.com
Importance Limited information exists regarding the impact of pharmacotherapy in
pregnancy due to ethical concerns of unintended fetal harm. Yet, maternal prescriptive drug …

COVID-19 pandemic quarantines and mental health among adolescents in Norway

JH Pettersen, LJ Hannigan, K Gustavson… - JAMA Network …, 2024 - jamanetwork.com
Importance Adolescence is a critical developmental phase when mental health disorders,
such as anxiety and depression, often emerge. Stringent public health measures and …

Body mass index and childhood symptoms of depression, anxiety, and attention-deficit hyperactivity disorder: A within-family Mendelian randomization study

AM Hughes, E Sanderson, T Morris, Z Ayorech, M Tesli… - elife, 2022 - elifesciences.org
Background: Higher BMI in childhood is associated with emotional and behavioural
problems, but these associations may not be causal. Results of previous genetic studies …

Parental education and children's depression, anxiety, and ADHD traits, a within-family study in MoBa

AM Hughes, FA Torvik, E van Bergen… - npj Science of …, 2024 - nature.com
Children born to parents with fewer years of education are more likely to have depression,
anxiety, and attention-deficit hyperactivity disorder (ADHD), but it is unclear to what extent …

[HTML][HTML] Intergenerational effects of parental educational attainment on parenting and childhood educational outcomes: Evidence from MoBa using within-family …

A Havdahl, AM Hughes, E Sanderson, H Ask… - medRxiv, 2023 - ncbi.nlm.nih.gov
The intergenerational transmission of educational attainment from parents to their children is
one of the most important and studied relationships in social science. Longitudinal studies …

Impaired glucose tolerance and cardiovascular risk factors in relation to infertility: a Mendelian randomization analysis in the Norwegian Mother, Father, and Child …

Á Hernáez, Y Lee, CM Page, KH Skåra… - Human …, 2024 - academic.oup.com
STUDY QUESTION Are impaired glucose tolerance (as measured by fasting glucose,
glycated hemoglobin, and fasting insulin) and cardiovascular disease risk (as measured by …

Examining intergenerational risk factors for conduct problems using polygenic scores in the Norwegian Mother, Father and Child Cohort Study

L Frach, W Barkhuizen, AG Allegrini, H Ask… - Molecular …, 2024 - nature.com
The aetiology of conduct problems involves a combination of genetic and environmental
factors, many of which are inherently linked to parental characteristics given parents' central …