Mycobacterium abscessus Infections in Cystic Fibrosis Individuals: A Review on Therapeutic Options

D Recchia, G Stelitano, A Stamilla… - International Journal of …, 2023 - mdpi.com
Mycobacterium abscessus is an opportunistic pathogen that mainly colonizes and infects
cystic fibrosis patients' lungs. M. abscessus is naturally resistant to many antibiotics such as …

The cell envelope of Mycobacterium abscessus and its role in pathogenesis

S Parmar, EI Tocheva - PLoS Pathogens, 2023 - journals.plos.org
Mycobacterium abscessus is a nontuberculosis mycobacterium (NTM) that has shown an
exponential rise in its ability to cause disease. Due to its ubiquitous presence in the …

Mycobacterium abscessus strain morphotype determines phage susceptibility, the repertoire of therapeutically useful phages, and phage resistance

RM Dedrick, BE Smith, RA Garlena, DA Russell… - MBio, 2021 - Am Soc Microbiol
Mycobacterium abscessus is an opportunistic pathogen whose treatment is confounded by
widespread multidrug resistance. The therapeutic use of bacteriophages against …

Genome-Wide Essentiality Analysis of Mycobacterium abscessus by Saturated Transposon Mutagenesis and Deep Sequencing

D Rifat, L Chen, BN Kreiswirth, EL Nuermberger - Mbio, 2021 - Am Soc Microbiol
Mycobacterium abscessus is an emerging opportunistic human pathogen that naturally
resists most major classes of antibiotics, making infections difficult to treat. Thus far, little is …

Designing a multi-epitope vaccine against Mycobacteroides abscessus by pangenome-reverse vaccinology

HA Dar, S Ismail, Y Waheed, S Ahmad, Z Jamil… - Scientific reports, 2021 - nature.com
Abstract Mycobacteroides abscessus (Previously Mycobacterium abscessus) is an emerging
microorganism of the newly defined genera Mycobacteroides that causes mainly skin and …

Updated Review on the Mechanisms of Pathogenicity in Mycobacterium abscessus, a Rapidly Growing Emerging Pathogen

P López-Roa, J Esteban, MC Muñoz-Egea - Microorganisms, 2022 - mdpi.com
In recent years, Mycobacterium abscessus has appeared as an emerging pathogen, with an
increasing number of disease cases reported worldwide that mainly occur among patients …

A Rough Colony Morphology of Mycobacterium abscessus Is Associated With Cavitary Pulmonary Disease and Poor Clinical Outcome

W Hedin, G Fröberg, K Fredman… - The Journal of …, 2023 - academic.oup.com
Abstract Background The Mycobacterium abscessus complex (MABC) is a difficult to treat
mycobacterium with two distinct morphologies: smooth and rough. As the clinical …

Antimicrobial activity of neutrophils against mycobacteria

HA Parker, L Forrester, CD Kaldor, N Dickerhof… - Frontiers in …, 2021 - frontiersin.org
The mycobacterium genus contains a broad range of species, including the human
pathogens M. tuberculosis and M. leprae. These bacteria are best known for their residence …

The use of amikacin liposome inhalation suspension (Arikayce) in the treatment of refractory nontuberculous mycobacterial lung disease in adults

O Khan, N Chaudary - Drug design, development and therapy, 2020 - Taylor & Francis
Nontuberculous mycobacteria (NTM) can cause and perpetuate chronic inflammation and
lung infection. Despite having the diagnostic criteria, as defined by the American Thoracic …

Phage therapy for nontuberculous mycobacteria: challenges and opportunities

GF Hatfull - Pulmonary Therapy, 2023 - Springer
Non-tuberculous mycobacterium (NTM) infections are often clinically challenging, with
lengthy antibiotic regimens that fail to resolve the infections with few good outcomes …